WormBase Tree Display for Gene: WBGene00004298
expand all nodes | collapse all nodes | view schema
WBGene00004298 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | CHROMOSOME_I | ||||||
Identity | Version | 2 | |||||||
Name | CGC_name | rad-54.L | Person_evidence | WBPerson195 | |||||
WBPerson1720 | |||||||||
Sequence_name | W06D4.6 | ||||||||
Molecular_name | W06D4.6 | ||||||||
W06D4.6.1 | |||||||||
CE25143 | |||||||||
Other_name | rad-54 | ||||||||
CELE_W06D4.6 | Accession_evidence | NDB | BX284601 | ||||||
Public_name | rad-54.L | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 04 Jul 2019 12:06:02 | WBPerson1983 | Name_change | CGC_name | rad-54.L | ||||
Other_name | rad-54 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | rad | ||||||||
Allele (58) | |||||||||
Strain | WBStrain00035848 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (12) | |||||||||
Ortholog (38) | |||||||||
Paralog (19) | |||||||||
Structured_description | Concise_description | rad-54 encodes a protein that belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, and human RAD54L, proteins known to be involved in the homologous recombination (HR) and repair of DNA; in elegans, rad-54 acts in a HR pathway, downstream of a nucleotide excision repair (NER) pathway, to promote ultraviolet induced apoptosis of damaged cells. | Paper_evidence | WBPaper00037879 | |||||
WBPaper00035885 | |||||||||
Curator_confirmed | WBPerson1823 | ||||||||
WBPerson567 | |||||||||
WBPerson324 | |||||||||
Date_last_updated | 09 Sep 2013 00:00:00 | ||||||||
Automated_description | Enables ATP-dependent activity, acting on DNA. Predicted to be involved in double-strand break repair via synthesis-dependent strand annealing and reciprocal meiotic recombination. Located in nucleus. Human ortholog(s) of this gene implicated in breast cancer; non-Hodgkin lymphoma; and pancreatic cancer. Is an ortholog of human RAD54L (RAD54 like). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0060060 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||
DOID:14566 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||||
DOID:1793 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||||
DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9826) | ||||||
Molecular_info | Corresponding_CDS | W06D4.6 | |||||||
Corresponding_transcript | W06D4.6.1 | ||||||||
Other_sequence (33) | |||||||||
Associated_feature | WBsf218248 | ||||||||
Experimental_info | RNAi_result (21) | ||||||||
Expr_pattern | Expr1013806 | ||||||||
Expr1032124 | |||||||||
Expr1158433 | |||||||||
Expr2015242 | |||||||||
Expr2033476 | |||||||||
Drives_construct | WBCnstr00007713 | ||||||||
WBCnstr00035582 | |||||||||
Construct_product | WBCnstr00007713 | ||||||||
WBCnstr00035582 | |||||||||
Microarray_results (20) | |||||||||
Expression_cluster (134) | |||||||||
Interaction (103) | |||||||||
Map_info | Map | I | Position | 3.48577 | Error | 0.010523 | |||
Positive | Positive_clone | W06D4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (22) | |||||||||
Remark | Sequence connection from [Boulton S, Vidal M] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |