WormBase Tree Display for Gene: WBGene00017082
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WBGene00017082 | SMap | S_parent | Sequence | DC2 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | Sequence_name | DC2.5 | |||||||
Molecular_name | DC2.5a | ||||||||
DC2.5a.1 | |||||||||
CE42420 | |||||||||
DC2.5b | |||||||||
Other_name | CELE_DC2.5 | Accession_evidence | NDB | BX284605 | |||||
Public_name | DC2.5 | ||||||||
DB_info | Database | AceView | gene | 5A688 | |||||
WormQTL | gene | WBGene00017082 | |||||||
WormFlux | gene | WBGene00017082 | |||||||
NDB | locus_tag | CELE_DC2.5 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00017082|UniProtKB=Q9UAW2 | |||||||
family | PTHR24320 | ||||||||
NCBI | gene | 183970 | |||||||
RefSeq | protein | NM_070754.6 | |||||||
NR_132472.1 | |||||||||
TrEMBL | UniProtAcc | Q9UAW2 | |||||||
UniProt_GCRP | UniProtAcc | Q9UAW2 | |||||||
OMIM | gene | 605131 | |||||||
RNAcentral | URSid | URS000084F687 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Allele (48) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00100722 | ||||||||
Ortholog (33) | |||||||||
Paralog (11) | |||||||||
Structured_description | Automated_description | Enriched in several structures, including ABplpppapa; ABprpppapa; anal sphincter muscle; rectal epithelial cell; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including TPEN; Alovudine; and stavudine based on RNA-seq; proteomic; and microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; short chain dehydrogenase; and NAD(P)-binding domain superfamily. Is an ortholog of human WWOX (WW domain containing oxidoreductase). | Paper_evidence | WBPaper00065943 | |||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:3748 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | ||||
DOID:5041 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | ||||||
DOID:0080452 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | ||||||
DOID:0080060 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | ||||||
DOID:1749 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | ||||||
Molecular_info (5) | |||||||||
Experimental_info | RNAi_result | WBRNAi00043540 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00012615 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr1025881 | ||||||||
Expr1037341 | |||||||||
Expr1147532 | |||||||||
Expr2002107 | |||||||||
Expr2020332 | |||||||||
Microarray_results (15) | |||||||||
Expression_cluster (212) | |||||||||
Interaction | WBInteraction000471081 | ||||||||
WBInteraction000585656 | |||||||||
Map_info | Positive | Positive_clone | DC2 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
Interpolated_map_position | V | -20.0099 | |||||||
Reference | WBPaper00038491 | ||||||||
WBPaper00055090 | |||||||||
Method | Gene |