WormBase Tree Display for Gene: WBGene00004310

WBGene00004310 SMap: S_parent: Sequence: C44C11
  Identity: Version: 1
    Name: CGC_name: ras-1
      Sequence_name: C44C11.1
      Molecular_name: C44C11.1a
        C44C11.1a.1
        CE24846
        C44C11.1b
      Other_name: R-ras1 Accession_evidence: EMBL U56933
        ras1 Accession_evidence: EMBL U56930
        CELE_C44C11.1 Accession_evidence: NDB BX284602
      Public_name: ras-1
    DB_info: Database: AceView gene 2M636
        WormQTL gene WBGene00004310
        WormFlux gene WBGene00004310
        NDB locus_tag CELE_C44C11.1
        Panther gene CAEEL|WormBase=WBGene00004310|UniProtKB=G5EBK8
          family PTHR24070
        NCBI gene 174875
        RefSeq protein NM_064222.7
            NR_051787.1
        TrEMBL UniProtAcc G5EBK8
        UniProt_GCRP UniProtAcc G5EBK8
        OMIM gene 600098
        RNAcentral URSid URS00000A761E
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ras
    Allele (209)
    Strain: WBStrain00035764
      WBStrain00035779
      WBStrain00035962
    Component_of_genotype: WBGenotype00000028
      WBGenotype00000029
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog: WBGene00054515 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00039840 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00152615 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00124587 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00223021 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g7470 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP26.g4197 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g14681 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g9764 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g26644 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g3672 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g11430 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g13998 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g7393 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g5752 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-ras-1 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g16785 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00080.g3638 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_09853 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_006680 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g11044 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g7684 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_20051700 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g6142 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00246647 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00203549 Pristionchus pacificus From_analysis: WormBase-Compara
      SGD:S000005627 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
            SonicParanoid
      SGD:S000005042 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
            SonicParanoid
      FB:FBgn0003206 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-041010-217 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050417-352 Danio rerio From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:10447 Homo sapiens From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:17271 Homo sapiens From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:98179 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1914172 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1311443 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1310793 Rattus norvegicus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog (14)
    Structured_description: Concise_description: ras-1 is orthologous to the human oncogene, Related Ras Viral Oncogene Homolog 2 (RRAS2). Paper_evidence: WBPaper00027296
          Curator_confirmed: WBPerson324
            WBPerson567
          Date_last_updated: 22 May 2012 00:00:00
      Automated_description: Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in parturition and vulval development. Predicted to be located in plasma membrane. Used to study RASopathy. Human ortholog(s) of this gene implicated in Noonan syndrome 12. Is an ortholog of human RRAS (RAS related) and RRAS2 (RAS related 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:0080690
    Potential_model: DOID:0112170 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:17271)
  Models_disease_asserted: WBDOannot00000070
    WBDOannot00000498
  Molecular_info: Corresponding_CDS: C44C11.1a
    Corresponding_CDS_history: C44C11.1b:wp213
    Corresponding_transcript: C44C11.1b
      C44C11.1a.1
    Other_sequence (29)
    Associated_feature (17)
  Experimental_info: RNAi_result: WBRNAi00107767 Inferred_automatically: RNAi_primary
      WBRNAi00093194 Inferred_automatically: RNAi_primary
      WBRNAi00027673 Inferred_automatically: RNAi_primary
      WBRNAi00042456 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021680
      Expr1032135
      Expr1146448
      Expr2015260
      Expr2033494
    Construct_product: WBCnstr00022879
      WBCnstr00022880
    Microarray_results (27)
    Expression_cluster (152)
    Interaction (276)
  Map_info: Map: II Position: 9.67089 Error: 0.137485
    Positive: Positive_clone: C44C11 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4624
        4686
        5028
    Pseudo_map_position
  Reference: WBPaper00014284
    WBPaper00014573
    WBPaper00027296
    WBPaper00031857
    WBPaper00038491
    WBPaper00040813
    WBPaper00041771
    WBPaper00042598
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene