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WormBase Tree Display for Gene: WBGene00020268

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Name Class

WBGene00020268SMapS_parentSequenceT05H4
IdentityVersion2
NameCGC_namehpo-19Paper_evidenceWBPaper00038231
Person_evidenceWBPerson26
Sequence_nameT05H4.5
Molecular_nameT05H4.5
T05H4.5.1
CE13277
Other_nameCELE_T05H4.5Accession_evidenceNDBBX284605
Public_namehpo-19
DB_infoDatabaseAceViewgene5G917
WormQTLgeneWBGene00020268
WormFluxgeneWBGene00020268
NDBlocus_tagCELE_T05H4.5
PanthergeneCAEEL|WormBase=WBGene00020268|UniProtKB=O16521
familyPTHR19370
NCBIgene179029
RefSeqproteinNM_072237.7
KEGGKEGG_id1.6.2.2
NemaPathKEGG_id1.6.2.2
TREEFAMTREEFAM_IDTF314333
TrEMBLUniProtAccO16521
UniProt_GCRPUniProtAccO16521
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:02WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
226 Apr 2011 13:31:47WBPerson2970Name_changeCGC_namehpo-19
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhpo
Allele (34)
RNASeq_FPKM (74)
GO_annotation00028233
00028234
00028235
00028236
00028237
00028238
00124939
Contained_in_operonCEOP5112
Ortholog (50)
ParalogWBGene00020267Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00013123Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionThe T05H4.5 gene encodes an ortholog of the human gene NADH-CYTOCHROME B5 REDUCTASE (DIA1), which when mutated leads to methemoglobinemia (OMIM:250800).Paper_evidenceWBPaper00004637
Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable FAD binding activity. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in estrogen-receptor negative breast cancer and methemoglobinemia. Is an ortholog of human CYB5R1 (cytochrome b5 reductase 1); CYB5R2 (cytochrome b5 reductase 2); and CYB5R3 (cytochrome b5 reductase 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060076Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2873)
DOID:10783Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2873)
DOID:1612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2873)
Molecular_infoCorresponding_CDST05H4.5
Corresponding_transcriptT05H4.5.1
Other_sequence (25)
Associated_featureWBsf646879
WBsf661336
WBsf231879
Experimental_infoRNAi_resultWBRNAi00009126Inferred_automaticallyRNAi_primary
WBRNAi00026207Inferred_automaticallyRNAi_primary
WBRNAi00052592Inferred_automaticallyRNAi_primary
WBRNAi00088747Inferred_automaticallyRNAi_primary
WBRNAi00088640Inferred_automaticallyRNAi_primary
WBRNAi00090940Inferred_automaticallyRNAi_primary
WBRNAi00071536Inferred_automaticallyRNAi_primary
WBRNAi00035243Inferred_automaticallyRNAi_primary
WBRNAi00111686Inferred_automaticallyRNAi_primary
Expr_patternExpr1021433
Expr1038824
Expr1156206
Expr2012561
Expr2030798
Drives_constructWBCnstr00025251
Construct_productWBCnstr00025251
Microarray_results (23)
Expression_cluster (111)
InteractionWBInteraction000163435
WBInteraction000165104
WBInteraction000165107
WBInteraction000174116
WBInteraction000230121
WBInteraction000230421
WBInteraction000235102
WBInteraction000235408
WBInteraction000241674
WBInteraction000241873
WBInteraction000251568
WBInteraction000252700
WBInteraction000253011
WBInteraction000254687
WBInteraction000262113
WBInteraction000264639
WBInteraction000267333
WBInteraction000270488
WBInteraction000271510
WBInteraction000275798
WBInteraction000280966
WBInteraction000296763
WBInteraction000297698
WBInteraction000319866
WBInteraction000333211
WBInteraction000338846
WBInteraction000341349
WBInteraction000342016
WBInteraction000356248
WBInteraction000358738
WBInteraction000360088
WBInteraction000362744
WBInteraction000363825
WBInteraction000364072
WBInteraction000377667
WBInteraction000378877
WBInteraction000380069
WBInteraction000382213
WBInteraction000387073
WBInteraction000404769
WBInteraction000411836
WBInteraction000412851
WBInteraction000413576
WBInteraction000414644
WBInteraction000419870
WBInteraction000428965
WBInteraction000445553
WBInteraction000446790
WBInteraction000447141
WBInteraction000449486
WBInteraction000455028
WBInteraction000455254
WBInteraction000457154
WBInteraction000462948
WBInteraction000464602
WBInteraction000467463
WBInteraction000468167
WBInteraction000473780
WBInteraction000551816
WBInteraction000558465
WBInteraction000559456
WBInteraction000573898
WBInteraction000583486
WBInteraction000584999
WBInteraction000585785
Map_infoMapVPosition-0.168074Error0.002349
PositivePositive_cloneT05H4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00049152
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene