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WormBase Tree Display for Gene: WBGene00022459

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Name Class

WBGene00022459SMapS_parentSequenceY110A7A
IdentityVersion1
NameSequence_nameY110A7A.9
Molecular_nameY110A7A.9a
Y110A7A.9a.1
CE28105
Y110A7A.9b
CE37057
Y110A7A.9b.1
Y110A7A.9b.2
Y110A7A.9b.3
Other_nameCELE_Y110A7A.9Accession_evidenceNDBBX284601
Public_nameY110A7A.9
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
AlleleWBVar00536959
WBVar01282690
WBVar01902384
WBVar01499786
WBVar00333818
WBVar00333819
WBVar00333820
WBVar00333821
WBVar00333822
WBVar00333823
WBVar00333824
WBVar00333825
WBVar00333826
WBVar00333827
WBVar00333828
WBVar00333829
WBVar00333830
WBVar00636201
WBVar00636202
WBVar00636203
WBVar00636204
WBVar00636205
WBVar00636206
WBVar00636207
WBVar00636208
WBVar00636209
WBVar00636210
WBVar00636211
WBVar00636212
WBVar00636213
WBVar00636214
WBVar00636215
WBVar00636216
WBVar00636217
WBVar00636218
WBVar00636219
WBVar00636220
WBVar00636221
WBVar00636222
WBVar00636223
WBVar00636224
WBVar00636225
WBVar00636226
WBVar00636227
WBVar00636228
WBVar01911723
WBVar00636229
WBVar00636230
WBVar00636231
WBVar00636232
WBVar00636233
WBVar00636234
WBVar01490675
WBVar01498959
StrainWBStrain00003412
RNASeq_FPKM (74)
GO_annotation00022044
Ortholog (39)
Structured_descriptionConcise_descriptionY110A7A.9 is orthologous to the human WD Repeat-Containing Protein 11(WDR11) which has 6 putative WD40 repeats, a predicted transmembrane region and a tyrosine kinase phosphorylation site; WDR11 is believed to be a tumor suppressor gene.Paper_evidenceWBPaper00038491
Curator_confirmedWBPerson324
WBPerson1823
WBPerson567
Date_last_updated25 Jul 2012 00:00:00
Automated_descriptionPredicted to be located in cytoplasm. Expressed in head. Used to study high grade glioma. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder and hypogonadotropic hypogonadism 14 with or without anosmia. Is an ortholog of human WDR11 (WD repeat domain 11).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:3070Homo sapiensPaper_evidenceWBPaper00038491
Curator_confirmedWBPerson324
Date_last_updated01 May 2023 00:00:00
Potential_modelDOID:0090087Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:13831)
DOID:0060308Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:13831)
Disease_relevanceY110A7A.9 is orthologous to the human WD Repeat-Containing Protein 11(WDR11), which is believed to be a tumor suppressor gene, alterations of which are involved in tumorigenesis of glial and other tumors.Homo sapiensAccession_evidenceOMIM606417
Curator_confirmedWBPerson324
Date_last_updated25 Jul 2012 00:00:00
Models_disease_in_annotationWBDOannot00000093
Molecular_infoCorresponding_CDSY110A7A.9a
Y110A7A.9b
Corresponding_CDS_historyY110A7A.9:wp126
Corresponding_transcriptY110A7A.9a.1
Y110A7A.9b.1
Y110A7A.9b.2
Y110A7A.9b.3
Other_sequence (35)
Associated_featureWBsf643268
WBsf643269
WBsf656285
WBsf976688
WBsf976689
WBsf976690
WBsf976691
WBsf976692
WBsf1009769
WBsf217624
Experimental_infoRNAi_resultWBRNAi00117128Inferred_automaticallyRNAi_primary
WBRNAi00078501Inferred_automaticallyRNAi_primary
WBRNAi00036560Inferred_automaticallyRNAi_primary
WBRNAi00078502Inferred_automaticallyRNAi_primary
WBRNAi00002406Inferred_automaticallyRNAi_primary
WBRNAi00004526Inferred_automaticallyRNAi_primary
WBRNAi00055330Inferred_automaticallyRNAi_primary
Expr_patternChronogram371
Expr6883
Expr1018563
Expr1039923
Expr1158870
Expr2007016
Expr2025242
Drives_constructWBCnstr00003879
WBCnstr00024225
Construct_productWBCnstr00024225
Microarray_results (23)
Expression_cluster (65)
Map_infoPositivePositive_cloneY110A7AInferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionI-0.399393
ReferenceWBPaper00033118
WBPaper00038491
WBPaper00055090
WBPaper00064339
MethodGene