WormBase Tree Display for Gene: WBGene00017437
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WBGene00017437 | SMap | S_parent | Sequence | F13H8 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | nmgp | ||||||
Allele | WBVar01499702 | ||||||
WBVar00737024 | |||||||
WBVar00737025 | |||||||
WBVar00737026 | |||||||
WBVar00737027 | |||||||
WBVar00737028 | |||||||
WBVar00737029 | |||||||
WBVar00737030 | |||||||
WBVar00737031 | |||||||
WBVar00737032 | |||||||
WBVar00737033 | |||||||
WBVar00737034 | |||||||
WBVar00737035 | |||||||
WBVar00737036 | |||||||
WBVar00737037 | |||||||
WBVar00172573 | |||||||
WBVar01498435 | |||||||
WBVar00367814 | |||||||
WBVar00367815 | |||||||
WBVar00367816 | |||||||
WBVar00600901 | |||||||
WBVar01626618 | |||||||
WBVar00259250 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00064731 | ||||||
00064732 | |||||||
00064733 | |||||||
00122825 | |||||||
Contained_in_operon | CEOP2761 | ||||||
Ortholog (44) | |||||||
Structured_description | Concise_description | F13H8.4 encodes a homolog of the human neuronal membrane glycoproteins PLP1 (OMIM:300401, mutated in Pelizaeus-Merzbacher disease and spastic paraplegia), M6A (OMIM:601275), and M6B (OMIM:300051); the presence of a myelin-related protein in C. elegans is currently unexplained, but suggests that some evolutionary precursor of myelin may exist in invertebrates, perhaps involving septate junctions between cells. | Paper_evidence | WBPaper00028828 | |||
WBPaper00028839 | |||||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 11 Dec 2006 00:00:00 | ||||||
Automated_description | Predicted to be involved in neuron projection development. Predicted to be located in plasma membrane. Expressed in several structures, including cephalic sheath cell; neurons; somatic nervous system; tail ganglion; and ventral ganglion. Used to study depressive disorder. Human ortholog(s) of this gene implicated in Pelizaeus-Merzbacher disease and hereditary spastic paraplegia 2. Is an ortholog of human GPM6A (glycoprotein M6A); GPM6B (glycoprotein M6B); and PLP1 (proteolipid protein 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Experimental_model | DOID:1596 | Homo sapiens | Paper_evidence | WBPaper00062210 | ||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 20 Jul 2022 00:00:00 | ||||||
Potential_model | DOID:0110773 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9086) | |||
DOID:3210 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9086) | ||||
Models_disease_asserted | WBDOannot00001289 | ||||||
Molecular_info | Corresponding_CDS | F13H8.4 | |||||
Corresponding_CDS_history | F13H8.4:wp107 | ||||||
Corresponding_transcript | F13H8.4.1 | ||||||
Other_sequence (20) | |||||||
Associated_feature | WBsf644264 | ||||||
WBsf981207 | |||||||
WBsf988116 | |||||||
WBsf1012354 | |||||||
WBsf221413 | |||||||
Experimental_info | RNAi_result | WBRNAi00116236 | Inferred_automatically | RNAi_primary | |||
WBRNAi00044560 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00116239 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00116241 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00116237 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00116242 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00116238 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00030915 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00116240 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr16049 | ||||||
Expr1023498 | |||||||
Expr1037501 | |||||||
Expr1148517 | |||||||
Expr2014331 | |||||||
Expr2032572 | |||||||
Drives_construct | WBCnstr00027301 | ||||||
WBCnstr00042737 | |||||||
Construct_product | WBCnstr00027301 | ||||||
Microarray_results (19) | |||||||
Expression_cluster (172) | |||||||
Interaction | WBInteraction000269487 | ||||||
WBInteraction000312085 | |||||||
WBInteraction000379908 | |||||||
WBInteraction000388919 | |||||||
WBInteraction000455587 | |||||||
Map_info | Map | II | Position | -0.392446 | Error | 0.000747 | |
Positive | Positive_clone | F13H8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00038491 | ||||||
WBPaper00055090 | |||||||
WBPaper00062210 | |||||||
WBPaper00063593 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |