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WormBase Tree Display for Gene: WBGene00017082

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Name Class

WBGene00017082SMapS_parentSequenceDC2
IdentityVersion1
NameSequence_nameDC2.5
Molecular_nameDC2.5a
DC2.5a.1
CE42420
DC2.5b
Other_nameCELE_DC2.5Accession_evidenceNDBBX284605
Public_nameDC2.5
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
AlleleWBVar01499528
WBVar01499167
WBVar01516537
WBVar00200649
WBVar01970441
WBVar01499740
WBVar00200650
WBVar01688798
WBVar01498840
WBVar01499775
WBVar01772934
WBVar01499052
WBVar01772935
WBVar01772936
WBVar01772937
WBVar01772938
WBVar01772939
WBVar01772940
WBVar01457386
WBVar01457387
WBVar00977855
WBVar00977856
WBVar00977857
WBVar00977858
WBVar00977859
WBVar00977860
WBVar00977861
WBVar00977862
WBVar01901006
WBVar00977863
WBVar00977864
WBVar00977865
WBVar00977866
WBVar00977867
WBVar00977868
WBVar00977869
WBVar00977870
WBVar00255197
WBVar01543096
WBVar00447224
WBVar02080284
WBVar01734931
WBVar01734932
WBVar01734933
WBVar02031369
WBVar02031370
WBVar01734934
WBVar01734935
RNASeq_FPKM (74)
GO_annotation00100722
Ortholog (33)
Paralog (11)
Structured_descriptionAutomated_descriptionEnriched in several structures, including ABplpppapa; ABprpppapa; anal sphincter muscle; rectal epithelial cell; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including TPEN; Alovudine; and stavudine based on RNA-seq; proteomic; and microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; short chain dehydrogenase; and NAD(P)-binding domain superfamily. Is an ortholog of human WWOX (WW domain containing oxidoreductase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:3748Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:5041Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:0080452Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:0080060Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
DOID:1749Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12799)
Molecular_infoCorresponding_CDSDC2.5a
Corresponding_CDS_historyDC2.5:wp88
DC2.5:wp125
DC2.5:wp188
Corresponding_transcriptDC2.5b
DC2.5a.1
Other_sequenceOden_isotig21742
Associated_featureWBsf652436
WBsf668708
WBsf999097
WBsf999098
WBsf999099
WBsf1019030
WBsf1019031
WBsf233243
Experimental_infoRNAi_resultWBRNAi00043540Inferred_automaticallyRNAi_primary
WBRNAi00012615Inferred_automaticallyRNAi_primary
Expr_patternExpr1025881
Expr1037341
Expr1147532
Expr2002107
Expr2020332
Microarray_results (15)
Expression_cluster (212)
InteractionWBInteraction000471081
WBInteraction000585656
Map_infoPositivePositive_cloneDC2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionV-20.0099
Reference (2)
MethodGene