WormBase Tree Display for Gene: WBGene00010478
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| WBGene00010478 | SMap | S_parent | Sequence | K01G5 | ||
|---|---|---|---|---|---|---|
| Identity (6) | ||||||
| Gene_info | Biotype | SO:0001217 | ||||
| Gene_class | dkc | |||||
| Allele | WBVar01500260 | |||||
| WBVar00179112 | ||||||
| WBVar00179113 | ||||||
| WBVar00179114 | ||||||
| WBVar01499194 | ||||||
| WBVar00093892 | ||||||
| WBVar02123229 | ||||||
| WBVar01499774 | ||||||
| WBVar01499594 | ||||||
| WBVar01499595 | ||||||
| WBVar02124001 | ||||||
| WBVar02132687 | ||||||
| WBVar00858341 | ||||||
| WBVar00858342 | ||||||
| WBVar00858343 | ||||||
| WBVar00858344 | ||||||
| WBVar00858345 | ||||||
| WBVar00858346 | ||||||
| WBVar00408000 | ||||||
| WBVar00858347 | ||||||
| WBVar00408001 | ||||||
| WBVar00408002 | ||||||
| WBVar00858348 | ||||||
| WBVar00408003 | ||||||
| WBVar00858349 | ||||||
| WBVar00858350 | ||||||
| WBVar00408004 | ||||||
| WBVar00408005 | ||||||
| WBVar00858351 | ||||||
| WBVar00858352 | ||||||
| WBVar00858353 | ||||||
| WBVar00858354 | ||||||
| WBVar00858355 | ||||||
| WBVar00858356 | ||||||
| Strain | WBStrain00037243 | |||||
| RNASeq_FPKM (74) | ||||||
| GO_annotation (18) | ||||||
| Contained_in_operon | CEOP3842 | |||||
| Ortholog (36) | ||||||
| Structured_description | Concise_description | The K01G5.5 gene encodes an ortholog of human DYSKERIN (DKC1; OMIM:300126), which when mutated leads to X-linked dyskeratosis congenita (OMIM:305000); the K01G5.5 protein is predicted to be mitochondrial with 68% accuracy. | Paper_evidence | WBPaper00004103 | ||
| WBPaper00004424 | ||||||
| Curator_confirmed | WBPerson1823 | |||||
| WBPerson567 | ||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | |||||
| Automated_description | Predicted to enable pseudouridine synthase activity. Predicted to be involved in box H/ACA RNA 3'-end processing and pseudouridine synthesis. Predicted to be located in nucleolus. Predicted to be part of box H/ACA snoRNP complex. Human ortholog(s) of this gene implicated in X-linked dyskeratosis congenita and aplastic anemia. Is an ortholog of human DKC1 (dyskerin pseudouridine synthase 1). | Paper_evidence | WBPaper00065943 | |||
| Curator_confirmed | WBPerson324 | |||||
| WBPerson37462 | ||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
| Date_last_updated | 29 Nov 2023 00:00:00 | |||||
| Disease_info | Potential_model | DOID:2729 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2890) | |
| DOID:12449 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2890) | |||
| DOID:0070025 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2890) | |||
| Molecular_info | Corresponding_CDS | K01G5.5 | ||||
| Corresponding_transcript | K01G5.5.1 | |||||
| Other_sequence (91) | ||||||
| Associated_feature | WBsf047618 | |||||
| WBsf645579 | ||||||
| WBsf659539 | ||||||
| WBsf976018 | ||||||
| WBsf976019 | ||||||
| WBsf981573 | ||||||
| WBsf994137 | ||||||
| WBsf225757 | ||||||
| WBsf225758 | ||||||
| WBsf225759 | ||||||
| Experimental_info | RNAi_result | WBRNAi00016410 | Inferred_automatically | RNAi_primary | ||
| WBRNAi00049635 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00002578 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00033832 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00001600 | Inferred_automatically | RNAi_primary | ||||
| WBRNAi00007830 | Inferred_automatically | RNAi_primary | ||||
| Expr_pattern | Expr1027254 | |||||
| Expr1034573 | ||||||
| Expr1153363 | ||||||
| Expr2004655 | ||||||
| Expr2022883 | ||||||
| Drives_construct | WBCnstr00031390 | |||||
| Construct_product | WBCnstr00031390 | |||||
| Microarray_results (19) | ||||||
| Expression_cluster (163) | ||||||
| Interaction (397) | ||||||
| Map_info | Map | III | Position | 5.19412 | ||
| Positive | Positive_clone | K01G5 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
| Pseudo_map_position | ||||||
| Reference | WBPaper00026935 | |||||
| WBPaper00030479 | ||||||
| WBPaper00031949 | ||||||
| WBPaper00038491 | ||||||
| WBPaper00049828 | ||||||
| WBPaper00054284 | ||||||
| WBPaper00055090 | ||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
| Method | Gene |
