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WormBase Tree Display for Gene: WBGene00008149

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Name Class

WBGene00008149SMapS_parentSequenceC47E12
IdentityVersion2
NameCGC_namepyp-1Person_evidenceWBPerson756
WBPerson268
Sequence_nameC47E12.4
Molecular_nameC47E12.4a
C47E12.4a.1
CE33767
C47E12.4c
CE48296
C47E12.4d
CE05448
C47E12.4c.1
C47E12.4d.1
Other_nameCELE_C47E12.4Accession_evidenceNDBBX284604
Public_namepyp-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:48WBPerson1971EventImportedInitial conversion from CDS class of WS125
209 Sep 2005 11:08:45WBPerson2970Name_changeCGC_namepyp-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpyp
AlleleWBVar00090875Inferred_automaticallyFrom strain object: MT14910
WBVar00088097
WBVar01730531
WBVar01500079
WBVar00935207
WBVar00935208
WBVar00935209
WBVar00935210
WBVar01453826
WBVar00935211
WBVar00935212
WBVar00935213
WBVar00935214
WBVar00935215
WBVar00935216
WBVar00935217
WBVar00935218
WBVar00935219
WBVar00935220
WBVar01498996
WBVar01499925
WBVar01499444
WBVar01499445
WBVar00191624
WBVar01856527
WBVar01856528
WBVar01856529
WBVar00433234
WBVar00433235
WBVar00433236
WBVar00433237
WBVar00433238
WBVar00261100
WBVar00433239
WBVar00433240
WBVar00433241
WBVar00433242
WBVar01500245
StrainWBStrain00027494
RNASeq_FPKM (74)
GO_annotation (16)
Contained_in_operonCEOP4348
Ortholog (49)
Structured_descriptionConcise_descriptionpyp-1 encodes, by alternative splicing, three isoforms of an inorganic pyrophosphatase required for embryonic and larval viability, intestinal function, and distal tip cell migration; PYP-1 is catalytically active in vitro, and is expressed in neurons, intestine, and coelomocytes; PYP-1 is orthologous to Drosophila NURF-38, and to human PPA1 (OMIM:179030) and PPA2; by orthology with NURF-38, PYP-1 is also predicted to participate in nucleosome remodelling.Paper_evidenceWBPaper00027681
WBPaper00028783
WBPaper00031169
WBPaper00031236
Curator_confirmedWBPerson567
Date_last_updated26 Nov 2007 00:00:00
Automated_descriptionPredicted to enable inorganic diphosphate phosphatase activity. Involved in innate immune response. Located in neuron projection and vacuole. Expressed in coelomocyte and neurons. Is an ortholog of human PPA1 (inorganic pyrophosphatase 1) and PPA2 (inorganic pyrophosphatase 2).Paper_evidenceWBPaper00065943
Curator_confirmed (2)
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC47E12.4a
C47E12.4c
C47E12.4d
Corresponding_CDS_historyC47E12.4:wp99
C47E12.4b:wp236
C47E12.4b:wp261
C47E12.4c:wp236
Corresponding_transcriptC47E12.4a.1
C47E12.4c.1
C47E12.4d.1
Other_sequence (133)
Associated_feature (11)
Experimental_infoRNAi_result (19)
Expr_patternExpr7807
Expr1020480
Expr1033540
Expr1146667
Expr2015205
Expr2033439
Drives_constructWBCnstr00012939
WBCnstr00033204
Construct_productWBCnstr00012939
WBCnstr00033204
AntibodyWBAntibody00001321
Microarray_results (41)
Expression_cluster (145)
Interaction (81)
Map_infoMapIVPosition4.46234Error0.00085
PositivePositive_cloneC47E12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (17)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene