WormBase Tree Display for Gene: WBGene00008132

WBGene00008132 SMap: S_parent: Sequence: C47B2
  Identity: Version: 2
    Name: CGC_name: gale-1 Person_evidence: WBPerson2629
            WBPerson1805
      Sequence_name: C47B2.6
      Molecular_name: C47B2.6a
        C47B2.6a.1
        CE17566
        C47B2.6b
        CE38295
        C47B2.6a.2
        C47B2.6b.1
        C47B2.6b.2
      Other_name: CELE_C47B2.6 Accession_evidence: NDB BX284601
      Public_name: gale-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 02 Feb 2007 17:11:41 WBPerson2970 Name_change: CGC_name: gale-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gale
    Allele: WBVar01350967
      WBVar00349356
      WBVar00349357
      WBVar01350978
      WBVar00349358
      WBVar01289116
      WBVar01664942
      WBVar00349359
      WBVar00349360
      WBVar01289122
      WBVar01289127
      WBVar00349361
      WBVar01428810
      WBVar00349362
      WBVar00349363
      WBVar01289131
      WBVar00349364
      WBVar01289132
      WBVar01289133
      WBVar01289135
      WBVar01289138
      WBVar01289141
      WBVar02055624
      WBVar01289142
      WBVar01434107
      WBVar01289143
      WBVar01434109
      WBVar01434110
      WBVar01403920
      WBVar01403923
      WBVar01948035
      WBVar01948039
      WBVar01948040
      WBVar01948041
      WBVar01948042
      WBVar01556481
      WBVar01499739
      WBVar01556482
      WBVar01556483
      WBVar02100026
      WBVar01556484
      WBVar02100027
      WBVar01993694
      WBVar01556485
      WBVar02100028
      WBVar01958495
      WBVar01495697
      WBVar01339453
      WBVar01353508
      WBVar01353519
      WBVar01353527
      WBVar01353529
      WBVar01476412
      WBVar01476413
      WBVar01476414
      WBVar00682393
      WBVar01641423
      WBVar00682394
      WBVar00682395
      WBVar00682396
      WBVar00682397
      WBVar00682398
      WBVar00682399
      WBVar00682400
      WBVar00682401
      WBVar00682402
      WBVar00252002
      WBVar00682403
      WBVar00682404
      WBVar00682405
      WBVar00682406
      WBVar00682407
      WBVar00682408
      WBVar00682409
      WBVar00682410
      WBVar00682411
      WBVar00682412
      WBVar00682413
      WBVar00682414
      WBVar00142350
      WBVar00682415
      WBVar00217478
      WBVar00682416
      WBVar00682417
      WBVar00682418
      WBVar00682419
      WBVar00682420
      WBVar00682421
      WBVar00682422
      WBVar00682423
      WBVar00682424
      WBVar00682425
      WBVar01499999
      WBVar00682426
      WBVar02128824
      WBVar02128825
      WBVar00682427
      WBVar02128826
      WBVar00682428
      WBVar00682429
      WBVar00682430
      WBVar00682431
      WBVar00682432
      WBVar00682433
      WBVar00682434
      WBVar01500560
      WBVar00682435
      WBVar00682436
      WBVar00682437
      WBVar01392598
      WBVar00682438
      WBVar00682439
      WBVar00682440
      WBVar01392601
      WBVar00682441
      WBVar00682442
      WBVar00682443
      WBVar00682444
      WBVar00682445
      WBVar00682446
      WBVar00682447
      WBVar00682448
      WBVar00682449
      WBVar00682450
      WBVar02095527
      WBVar02095528
      WBVar02141230
      WBVar00160088
      WBVar00160089
      WBVar00160090
      WBVar00160091
      WBVar00160092
      WBVar00160093
      WBVar00160094
      WBVar00306207
      WBVar00160095
      WBVar00160096
      WBVar00160097
      WBVar00160098
      WBVar00160099
      WBVar00541615
      WBVar00160100
      WBVar00160101
      WBVar00541621
      WBVar00160102
      WBVar00160103
      WBVar00160104
      WBVar00160105
      WBVar00160106
      WBVar02087088
      WBVar02087089
      WBVar01350934
      WBVar01497116
      WBVar00309658
      WBVar01350945
      WBVar01350956
      WBVar00349354
      WBVar00349355
    Strain: WBStrain00002441
      WBStrain00001620
    RNASeq_FPKM (74)
    GO_annotation (29)
    Contained_in_operon: CEOP1786
    Ortholog (38)
    Paralog (13)
    Structured_description (2)
  Disease_info: Experimental_model: DOID:9870 Homo sapiens Paper_evidence: WBPaper00045849
          Accession_evidence: OMIM 230350
          Curator_confirmed: WBPerson324
          Date_last_updated: 03 Oct 2018 00:00:00
    Potential_model: DOID:0111458 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:4116)
    Disease_relevance: Mutations in human GALE (UDP-galactose-4-prime-epimerase) are implicated in the autosomal recessive disorder, type III galactosemia; GALE participates in the galactose metabolism pathway, catalyzing the interconversion of UDP-galactose (UDP-gal) and UDP-glucose (UDP-glc) and in some species, including humans, also the interconversion of UDP-N-acetylgalactosamine (UDP-galNAc) and UDP-N-acetylglucosamine (UDP-glcNAc; one of the symptoms of galactosemia is intolerance to a galactose-rich diet, attributed to the accumulation of toxic galactose metabolism intermediates Homo sapiens Paper_evidence: WBPaper00045849
          Accession_evidence: OMIM 606953
          Curator_confirmed: WBPerson324
  Models_disease_in_annotation: WBDOannot00000322
  Molecular_info: Corresponding_CDS: C47B2.6a
      C47B2.6b
    Corresponding_transcript: C47B2.6a.1
      C47B2.6a.2
      C47B2.6b.1
      C47B2.6b.2
    Other_sequence (191)
    Associated_feature: WBsf657001
      WBsf657002
      WBsf218666
      WBsf218667
      WBsf218668
      WBsf218669
  Experimental_info: RNAi_result: WBRNAi00042653 Inferred_automatically: RNAi_primary
      WBRNAi00003176 Inferred_automatically: RNAi_primary
      WBRNAi00029897 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr5525
      Expr5526
      Expr1017938
      Expr1033529
      Expr1146641
      Expr2011938
      Expr2030175
    Drives_construct: WBCnstr00002459
      WBCnstr00004348
    Construct_product: WBCnstr00019730
    Microarray_results (25)
    Expression_cluster (209)
    Interaction (62)
    WBProcess: WBbiopr:00000046
  Map_info: Map: I Position: 16.8109 Error: 0.002729
    Positive: Positive_clone: C47B2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027024
    WBPaper00028564
    WBPaper00029024
    WBPaper00036792
    WBPaper00038491
    WBPaper00045849
    WBPaper00055090
    WBPaper00062922
    WBPaper00064651
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene