WormBase Tree Display for Gene: WBGene00007135

WBGene00007135 SMap: S_parent: Sequence: B0285
  Identity: Version: 4
    Name: CGC_name: cdk-12 Person_evidence: WBPerson313
            WBPerson3232
            WBPerson555
      Sequence_name: B0285.1
      Molecular_name (12)
      Other_name: cdtl-7 Person_evidence: WBPerson3232
            WBPerson555
        CELE_B0285.1 Accession_evidence: NDB BX284603
      Public_name: cdk-12
    DB_info: Database (14)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:47 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 02 Mar 2009 11:15:07 WBPerson9133 Name_change: CGC_name: cdtl-7
        3 23 Nov 2012 14:00:52 WBPerson2970 Name_change: CGC_name: cdk-12
        4 10 Jun 2014 12:12:12 WBPerson1983 Event: Acquires_merge: WBGene00043080
      Acquires_merge: WBGene00043080
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cdk
    Allele: WBVar00821211
      WBVar00821212
      WBVar00821213
      WBVar00821214
      WBVar00821215
      WBVar00821216
      WBVar01709969
      WBVar00821217
      WBVar00821218
      WBVar00821219
      WBVar00821220
      WBVar00821221
      WBVar00821222
      WBVar00821223
      WBVar00821224
      WBVar00821225
      WBVar00821226
      WBVar00301891
      WBVar00821227
      WBVar02131872
      WBVar00301892
      WBVar00821228
      WBVar02131873
      WBVar00301893
      WBVar00821229
      WBVar02131874
      WBVar00821230
      WBVar00821231
      WBVar00821232
      WBVar00821233
      WBVar00821234
      WBVar01994979
      WBVar02053228
      WBVar00821235
      WBVar00821236
      WBVar01994980
      WBVar01994981
      WBVar00821237
      WBVar00821238
      WBVar00821239
      WBVar00821240
      WBVar00821241
      WBVar00059221
      WBVar00821242
      WBVar01785416
      WBVar00821243
      WBVar01785417
      WBVar00821244
      WBVar00821245
      WBVar00821246
      WBVar00821247
      WBVar00821248
      WBVar00821249
      WBVar02010430
      WBVar00821250
      WBVar00821251
      WBVar00821252
      WBVar00821253
      WBVar00821254
      WBVar00821255
      WBVar00821256
      WBVar02067489
      WBVar00821257
      WBVar02067490
      WBVar00821258
      WBVar01628445
      WBVar00821259
      WBVar00821260
      WBVar00821261
      WBVar00821262
      WBVar00821263
      WBVar00821264
      WBVar01408497
      WBVar01408498
      WBVar00821265
      WBVar00821266
      WBVar00821267
      WBVar00052101
      WBVar00052106
      WBVar00275633
      WBVar01262958
      WBVar00296666
      WBVar01262960
      WBVar01396731
      WBVar01262961
      WBVar01262963
      WBVar01262965
      WBVar01823277
      WBVar02034126
      WBVar01823278
      WBVar02034127
      WBVar00395814
      WBVar00395815
      WBVar00395816
      WBVar00395817
      WBVar00395818
      WBVar00395819
      WBVar00395820
      WBVar00395821
      WBVar00395822
      WBVar00395823
      WBVar00395824
      WBVar00395825
      WBVar00395826
      WBVar01644045
      WBVar00395827
      WBVar00395828
      WBVar01644046
      WBVar00395829
      WBVar01644047
      WBVar00395830
      WBVar01644048
      WBVar01692357
      WBVar00236452
      WBVar01893201
      WBVar01837438
      WBVar01893202
      WBVar01938946
      WBVar01938947
      WBVar00255931
      WBVar01983887
      WBVar00252442
    Strain: WBStrain00003574
      WBStrain00024046
      WBStrain00024054
      WBStrain00024069
      WBStrain00024070
      WBStrain00037602
    RNASeq_FPKM (74)
    GO_annotation (24)
    Ortholog (38)
    Paralog (17)
    Structured_description: Automated_description: Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin binding activity. Involved in nematode larval development. Part of euchromatin. Expressed in several structures, including germ line and head. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; carcinoma (multiple); and congenital heart defects, dysmorphic facial features, and intellectual developmental disorder. Is an ortholog of human CDK13 (cyclin dependent kinase 13). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112247 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733)
      DOID:10534 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:24224)
      DOID:10286 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733)
      DOID:3717 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:24224)
      DOID:10283 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733,HGNC:24224)
      DOID:1059 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1733)
  Molecular_info: Corresponding_CDS: B0285.1a
      B0285.1b
      B0285.1c
    Corresponding_CDS_history: B0285.1:wp23
      B0285.1:wp83
    Corresponding_transcript: B0285.1a.1
      B0285.1a.2
      B0285.1b.1
      B0285.1b.2
      B0285.1c.1
      B0285.1c.2
    Other_sequence (19)
    Associated_feature (11)
  Experimental_info: RNAi_result (56)
    Expr_pattern (8)
    Drives_construct: WBCnstr00004026
      WBCnstr00033974
    Construct_product: WBCnstr00019156
      WBCnstr00019285
      WBCnstr00019286
      WBCnstr00019287
      WBCnstr00033974
    Microarray_results (26)
    Expression_cluster (96)
    Interaction (92)
  Map_info: Map: III Position: -3.18675 Error: 0.000933
    Positive: Positive_clone: B0285 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027258
    WBPaper00031224
    WBPaper00032961
    WBPaper00038491
    WBPaper00044000
    WBPaper00047409
    WBPaper00055090
    WBPaper00060756
    WBPaper00063946
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [140610 pad] Gene was missing Acquires_merge Event history data so inferred from Acquires_merge tag.
  Method: Gene