WormBase Tree Display for Gene: WBGene00004988
expand all nodes | collapse all nodes | view schema
WBGene00004988 | SMap | S_parent | Sequence | T08A9 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | spp | |||||
Allele | WBVar00508187 | |||||
WBVar00508188 | ||||||
WBVar00508189 | ||||||
WBVar01499933 | ||||||
WBVar01499934 | ||||||
WBVar00080407 | ||||||
WBVar00080408 | ||||||
WBVar01499760 | ||||||
WBVar01499761 | ||||||
WBVar01160009 | ||||||
WBVar01499867 | ||||||
WBVar01499868 | ||||||
WBVar01499685 | ||||||
WBVar01500067 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00074946 | |||||
00074947 | ||||||
00074948 | ||||||
00074949 | ||||||
00074950 | ||||||
Ortholog (25) | ||||||
Paralog (12) | ||||||
Structured_description | Concise_description | spp-3 encodes an antimicrobial peptide that belongs to the SPP-protein family, called caenopores, with structural similarity to saposin-like proteins (SAPLIPs), the amoebapores and the mammalian NK-lysin and granulysin; caenopores are part of the worm's innate immune system and interact with and eliminate bacteria via membrane pore-forming activity; C. elegans has at least 33 putative SPP proteins; in an heterologous expression system, spp-3 formed pores in liposomes, and showed antimicrobial activity against several gram- negative and positive bacteria such as E. coli, P. aeruginosa, Ph. luminescence, X. nematophila, Y. enterocolitica, B. megaterium and B. thuringiensis; spp-3 is expressed in the intestine and the SDQR head neuron. | Paper_evidence | WBPaper00041167 | ||
WBPaper00035289 | ||||||
Curator_confirmed | WBPerson324 | |||||
Date_last_updated | 17 Sep 2013 00:00:00 | |||||
Automated_description | Enables identical protein binding activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Located in protein-containing complex. Expressed in SDQR. | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Molecular_info | Corresponding_CDS | T08A9.7 | ||||
Corresponding_transcript | T08A9.7.1 | |||||
Other_sequence | CRC07887_1 | |||||
CBC05377_1 | ||||||
CR08323 | ||||||
CJC04748_1 | ||||||
Associated_feature | WBsf899530 | Paper_evidence | WBPaper00041167 | |||
WBsf899531 | Paper_evidence | WBPaper00041167 | ||||
WBsf899532 | Paper_evidence | WBPaper00041167 | ||||
WBsf899533 | Paper_evidence | WBPaper00041167 | ||||
WBsf1005803 | ||||||
WBsf1005804 | ||||||
WBsf1005805 | ||||||
WBsf1023225 | ||||||
WBsf237567 | ||||||
Experimental_info | RNAi_result | WBRNAi00082192 | Inferred_automatically | RNAi_primary | ||
WBRNAi00052828 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00092241 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00082199 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Expr10056 | |||||
Expr1028065 | ||||||
Expr1156430 | ||||||
Expr2016081 | ||||||
Expr2034317 | ||||||
Drives_construct | WBCnstr00015028 | |||||
WBCnstr00035289 | ||||||
Construct_product | WBCnstr00015028 | |||||
WBCnstr00035289 | ||||||
Microarray_results (17) | ||||||
Expression_cluster (211) | ||||||
Interaction (257) | ||||||
Map_info | Map | X | Position | -1.7753 | ||
Positive | Positive_clone | T08A9 | Inferred_automatically | From CDS info | ||
From sequence, transcript, pseudogene data | ||||||
Pseudo_map_position | ||||||
Reference | WBPaper00003435 | |||||
WBPaper00006437 | ||||||
WBPaper00024209 | ||||||
WBPaper00027295 | ||||||
WBPaper00028482 | ||||||
WBPaper00035289 | ||||||
WBPaper00041167 | ||||||
WBPaper00064841 | ||||||
WBPaper00065877 | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |