WormBase Tree Display for Gene: WBGene00004216

WBGene00004216 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: C24B5
  Identity (6)
  Gene_info: Biotype: SO:0001217
    Gene_class: ptr
    Allele: WBVar01461113
      WBVar02153661
      WBVar01499903
      WBVar00255989
      WBVar01500101
      WBVar00466046
      WBVar00466047
      WBVar00466048
      WBVar00466049
      WBVar00466050
      WBVar00466051
      WBVar00466052
      WBVar00466053
      WBVar00466054
      WBVar01500129
      WBVar01035049
      WBVar01035050
      WBVar01035051
      WBVar01035052
      WBVar01035053
      WBVar01035054
      WBVar01035055
      WBVar01035056
      WBVar01035057
      WBVar01035058
      WBVar01035059
      WBVar01035060
      WBVar01035061
      WBVar01035062
      WBVar01035063
      WBVar01035064
      WBVar01035065
      WBVar01035066
      WBVar01035067
      WBVar01035068
      WBVar00308246
      WBVar01499419
      WBVar01499420
      WBVar01499056
      WBVar01495383
      WBVar01742587
      WBVar01742588
      WBVar01498762
      WBVar01499316
    Strain: WBStrain00047651
    RNASeq_FPKM (74)
    GO_annotation: 00060255
      00060256
      00060257
      00060258
      00060259
      00060260
      00060261
      00112504
    Ortholog (34)
    Paralog (30)
    Structured_description: Concise_description: ptr-1 encodes an ortholog of Drosophila and human PTCHD3, which definesone of seven paralogous families of sterol sensing domain (SSD)proteins; individually, PTR-1 is weakly required for normal molting fromL4 to adult stages; however, PTR-1, in conjunction with either PTR-16alone or with PTR-6 and PTR-10, is strongly required for both moltingand viability, with double ptr-1/-16 or triple ptr-1/-6/-10 RNAi animalsshowing pronounced molting defects and lethality; PTR-1 is also requiredfor normal adult alae formation, growth to full size, locomotion, andmale tail development. Paper_evidence: WBPaper00006465
            WBPaper00024393
            WBPaper00026841
            WBPaper00027263
            WBPaper00028381
          Curator_confirmed: WBPerson567
          Date_last_updated: 08 Nov 2006 00:00:00
      Automated_description: Involved in molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Is an ortholog of human PTCHD3 (patched domain containing 3 (gene/pseudogene)). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C24B5.3
    Corresponding_transcript: C24B5.3.1
    Other_sequence (21)
    Associated_feature (12)
  Experimental_info: RNAi_result: WBRNAi00076909 Inferred_automatically: RNAi_primary
      WBRNAi00041068 Inferred_automatically: RNAi_primary
      WBRNAi00011088 Inferred_automatically: RNAi_primary
      WBRNAi00076941 Inferred_automatically: RNAi_primary
      WBRNAi00076933 Inferred_automatically: RNAi_primary
      WBRNAi00077030 Inferred_automatically: RNAi_primary
      WBRNAi00076965 Inferred_automatically: RNAi_primary
      WBRNAi00077029 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1025404
      Expr1032073
      Expr1145102
      Expr2015163
      Expr2033401
    Drives_construct: WBCnstr00035631
    Construct_product: WBCnstr00035631
    Microarray_results (18)
    Expression_cluster (209)
    Interaction (102)
  Map_info: Map: V Position: 1.94951 Error: 0.000146
    Positive: Positive_clone: C24B5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00004265
    WBPaper00005866
    WBPaper00026841
    WBPaper00033734
    WBPaper00038491
    WBPaper00055090
    WBPaper00064105
    WBPaper00065331
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene