WormBase Tree Display for Gene: WBGene00001690
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| WBGene00001690 | Evidence | Paper_evidence | WBPaper00003717 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | R08B4 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | grd-1 | Person_evidence | WBPerson83 | |||||
| Sequence_name | R08B4.1 | ||||||||
| Molecular_name | R08B4.1 | ||||||||
| R08B4.1.1 | |||||||||
| CE34080 | |||||||||
| R08B4.1.2 | |||||||||
| Other_name | CELE_R08B4.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | grd-1 | ||||||||
| DB_info | Database | AceView | gene | XL733 | |||||
| WormQTL | gene | WBGene00001690 | |||||||
| WormFlux | gene | WBGene00001690 | |||||||
| NDB | locus_tag | CELE_R08B4.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001690|UniProtKB=Q7YXC8 | |||||||
| family | PTHR46706 | ||||||||
| NCBI | gene | 181300 | |||||||
| RefSeq | protein | NM_001029672.3 | |||||||
| TrEMBL | UniProtAcc | Q21835 | |||||||
| UniProt_GCRP | UniProtAcc | Q21835 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | grd | ||||||||
| Allele | WBVar01185672 | ||||||||
| WBVar01185673 | |||||||||
| WBVar01185674 | |||||||||
| WBVar01499887 | |||||||||
| WBVar01185675 | |||||||||
| WBVar01987687 | |||||||||
| WBVar01185676 | |||||||||
| WBVar01499888 | |||||||||
| WBVar01185677 | |||||||||
| WBVar01185678 | |||||||||
| WBVar01185679 | |||||||||
| WBVar01185680 | |||||||||
| WBVar02144811 | |||||||||
| WBVar01185681 | |||||||||
| WBVar01499710 | |||||||||
| WBVar01185682 | |||||||||
| WBVar01185683 | |||||||||
| WBVar01185684 | |||||||||
| WBVar01185685 | |||||||||
| WBVar01185686 | |||||||||
| WBVar01185687 | |||||||||
| WBVar00600849 | |||||||||
| WBVar01185688 | |||||||||
| WBVar01185689 | |||||||||
| WBVar01185690 | |||||||||
| WBVar01185691 | |||||||||
| WBVar01185692 | |||||||||
| WBVar01185693 | |||||||||
| WBVar01185694 | |||||||||
| WBVar01185695 | |||||||||
| WBVar01185696 | |||||||||
| WBVar01185697 | |||||||||
| WBVar01185698 | |||||||||
| WBVar01185699 | |||||||||
| WBVar01185700 | |||||||||
| WBVar01907915 | |||||||||
| WBVar01928285 | |||||||||
| WBVar01690255 | |||||||||
| WBVar01690256 | |||||||||
| WBVar01690257 | |||||||||
| WBVar01690258 | |||||||||
| WBVar00303792 | |||||||||
| WBVar01471064 | |||||||||
| WBVar01759399 | |||||||||
| WBVar01471065 | |||||||||
| WBVar01759400 | |||||||||
| WBVar01759401 | |||||||||
| WBVar01759402 | |||||||||
| WBVar01759403 | |||||||||
| WBVar00249760 | |||||||||
| WBVar00516688 | |||||||||
| WBVar00516689 | |||||||||
| WBVar00516690 | |||||||||
| WBVar00516691 | |||||||||
| WBVar00516692 | |||||||||
| WBVar00516693 | |||||||||
| WBVar00516694 | |||||||||
| WBVar00516695 | |||||||||
| WBVar00516696 | |||||||||
| WBVar00516697 | |||||||||
| WBVar00516698 | |||||||||
| WBVar00516699 | |||||||||
| WBVar00516700 | |||||||||
| WBVar00516701 | |||||||||
| WBVar01703413 | |||||||||
| WBVar01787021 | |||||||||
| WBVar00067455 | |||||||||
| WBVar00067460 | |||||||||
| WBVar00067465 | |||||||||
| WBVar02027401 | |||||||||
| WBVar00083005 | |||||||||
| WBVar00083007 | |||||||||
| WBVar00083009 | |||||||||
| WBVar01602174 | |||||||||
| WBVar01185656 | |||||||||
| WBVar01185657 | |||||||||
| WBVar01185658 | |||||||||
| WBVar01185659 | |||||||||
| WBVar01185660 | |||||||||
| WBVar01185661 | |||||||||
| WBVar00091964 | |||||||||
| WBVar01185662 | |||||||||
| WBVar01185663 | |||||||||
| WBVar01185664 | |||||||||
| WBVar01185665 | |||||||||
| WBVar01185666 | |||||||||
| WBVar01185667 | |||||||||
| WBVar01185668 | |||||||||
| WBVar01498960 | |||||||||
| WBVar01185669 | |||||||||
| WBVar01185670 | |||||||||
| WBVar01185671 | |||||||||
| WBVar01500067 | |||||||||
| Strain | WBStrain00035810 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (3) | |||||||||
| Ortholog (42) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | grd-1 encodes a hedgehog-like protein, with (from N- to C-terminus) asignal sequence, a Ground domain, an extended region of low-complexitysequence, and a Hint/Hog domain; GRD-1 is expressed in rectal cells; theHint/Hog domain is predicted to cut GRD-1 into two halves and thencovalently link cholesterol to the C-terminus of the Ground domain; theGround domain is predicted to form a cysteine-crosslinked proteininvolved in intercellular signalling, and it has subtle similarity tothe N-terminal Hedge domain of HEDGEHOG proteins; GRD-1 is weaklyrequired for normal molting; GRD-1 is also required for normal growth tofull size, cuticle adhesion, and male tail development; all of theserequirements may reflect common defects in cholesterol-dependenthedgehog-like signalling or in vesicle trafficking. | Paper_evidence | WBPaper00003717 | |||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 05 Nov 2006 00:00:00 | ||||||||
| Automated_description | Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in extracellular region. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R08B4.1 | |||||||
| Corresponding_CDS_history | R08B4.1:wp52 | ||||||||
| R08B4.1:wp83 | |||||||||
| R08B4.1:wp101 | |||||||||
| R08B4.1b:wp272 | |||||||||
| Corresponding_transcript | R08B4.1.1 | ||||||||
| R08B4.1.2 | |||||||||
| Other_sequence (17) | |||||||||
| Associated_feature | WBsf648520 | ||||||||
| WBsf648521 | |||||||||
| WBsf1023814 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00076990 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00077015 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00051525 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00017576 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00111006 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr633 | ||||||||
| Expr4417 | |||||||||
| Expr1026738 | |||||||||
| Expr1031009 | |||||||||
| Expr1155201 | |||||||||
| Expr2012231 | |||||||||
| Expr2030467 | |||||||||
| Drives_construct | WBCnstr00011978 | ||||||||
| WBCnstr00012457 | |||||||||
| WBCnstr00036766 | |||||||||
| Construct_product | WBCnstr00036766 | ||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (197) | |||||||||
| Interaction | WBInteraction000114598 | ||||||||
| WBInteraction000114599 | |||||||||
| WBInteraction000114607 | |||||||||
| WBInteraction000173618 | |||||||||
| WBInteraction000237583 | |||||||||
| WBProcess | WBbiopr:00000123 | ||||||||
| Map_info | Map | X | Position | 2.85852 | Error | 0.000413 | |||
| Positive | Positive_clone | R08B4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4384 | |||||||
| 4421 | |||||||||
| 5511 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
