WormBase Tree Display for Gene: WBGene00001579

WBGene00001579 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 1
    Name: CGC_name: gex-2 Person_evidence: WBPerson419
      Sequence_name: F56A11.1
      Molecular_name (3)
      Other_name: CELE_F56A11.1 Accession_evidence: NDB BX284604
      Public_name: gex-2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gex
    Allele: WBVar00881413
      WBVar00881414
      WBVar01823389
      WBVar01823390
      WBVar01823391
      WBVar01828035
      WBVar01828036
      WBVar01828037
      WBVar01828038
      WBVar01499166
      WBVar01984399
      WBVar01984400
      WBVar01984401
      WBVar00415626
      WBVar01984402
      WBVar00415627
      WBVar00415628
      WBVar01984403
      WBVar00415629
      WBVar00415630
      WBVar00415631
      WBVar00415632
      WBVar00415633
      WBVar00415634
      WBVar00415635
      WBVar00415636
      WBVar00415637
      WBVar00415638
      WBVar00415639
      WBVar00415640
      WBVar00415641
      WBVar00415642
      WBVar00415643
      WBVar00415644
      WBVar00415645
      WBVar01607824
      WBVar00415646
      WBVar01607825
      WBVar02048965
      WBVar00415647
      WBVar01607826
      WBVar01607827
      WBVar00415648
      WBVar01499384
      WBVar00415649
      WBVar01607828
      WBVar01499385
      WBVar01607829
      WBVar00415650
      WBVar01607830
      WBVar00415651
      WBVar01607831
      WBVar01607832
      WBVar01607833
      WBVar01607834
      WBVar01607835
      WBVar01607836
      WBVar01607837
      WBVar01607838
      WBVar01607839
      WBVar00265417
      WBVar01607840
      WBVar00002231
      WBVar01667621
      WBVar01667622
      WBVar00002236
      WBVar00253110
      WBVar01491881
      WBVar02050866
      WBVar02050867
      WBVar01450167
      WBVar01450168
      WBVar01450169
      WBVar01450170
      WBVar00881339
      WBVar00881340
      WBVar00881341
      WBVar00881342
      WBVar00881343
      WBVar00881344
      WBVar00881345
      WBVar01499633
      WBVar00881346
      WBVar00881347
      WBVar00881348
      WBVar00881349
      WBVar00881350
      WBVar00263634
      WBVar00881351
      WBVar00881352
      WBVar00881353
      WBVar00881354
      WBVar00881355
      WBVar02048116
      WBVar00881356
      WBVar00881357
      WBVar00881358
      WBVar00881359
      WBVar00881360
      WBVar00881361
      WBVar00881362
      WBVar00881363
      WBVar00881364
      WBVar00881365
      WBVar00881366
      WBVar01825550
      WBVar00881367
      WBVar01825551
      WBVar00881368
      WBVar00881369
      WBVar00881370
      WBVar00881371
      WBVar00881372
      WBVar00881373
      WBVar00881374
      WBVar00881375
      WBVar00881376
      WBVar00881377
      WBVar00881378
      WBVar00881379
      WBVar00881380
      WBVar00881381
      WBVar00881382
      WBVar00881383
      WBVar00881384
      WBVar00881385
      WBVar00881386
      WBVar01724608
      WBVar00881387
      WBVar00881388
      WBVar00881389
      WBVar00881390
      WBVar00881391
      WBVar01647023
      WBVar01647024
      WBVar00881392
      WBVar00881393
      WBVar02112114
      WBVar00881394
      WBVar00881395
      WBVar01499498
      WBVar00881396
      WBVar01499499
      WBVar00881397
      WBVar00881398
      WBVar00881399
      WBVar00881400
      WBVar00881401
      WBVar00092811
      WBVar00881402
      WBVar00881403
      WBVar00881404
      WBVar00881405
      WBVar00881406
      WBVar00881407
      WBVar00881408
      WBVar01499328
      WBVar00881409
      WBVar01499329
      WBVar00881410
      WBVar00881411
      WBVar00881412
    Strain: WBStrain00036391
    RNASeq_FPKM (74)
    GO_annotation (22)
    Ortholog (50)
    Structured_description: Concise_description: The gex-2 gene encodes a homolog of p140/Sra-1, a mammalian protein ligand of the small GTPase Rac1; gex-2 is required for tissue morphogenesis and cell migrations. Paper_evidence: WBPaper00005149
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable RNA 7-methylguanosine cap binding activity. Involved in several processes, including embryonic body morphogenesis; positive regulation of clathrin-dependent endocytosis; and positive regulation of egg-laying behavior. Located in cell junction. Part of SCAR complex. Human ortholog(s) of this gene implicated in several diseases, including Schaaf-Yang syndrome; autism spectrum disorder; and epilepsy (multiple). Is an ortholog of human CYFIP1 (cytoplasmic FMR1 interacting protein 1) and CYFIP2 (cytoplasmic FMR1 interacting protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111715 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13759)
      DOID:0080430 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13760)
      DOID:0060041 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13759)
      DOID:3328 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13759)
      DOID:5419 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:13759)
  Molecular_info: Corresponding_CDS: F56A11.1
    Corresponding_CDS_history: F56A11.1:wp129
    Corresponding_transcript: F56A11.1.1
    Other_sequence (56)
    Associated_feature: WBsf645763
      WBsf995193
      WBsf995194
      WBsf1016569
      WBsf227856
      WBsf227857
      WBsf227858
      WBsf227859
  Experimental_info: RNAi_result (33)
    Expr_pattern: Expr1827
      Expr1026712
      Expr1030945
      Expr1152359
      Expr2012023
      Expr2030259
    Drives_construct: WBCnstr00036849
    Construct_product: WBCnstr00036849
    Antibody: WBAntibody00000462
      WBAntibody00000463
    Microarray_results (20)
    Expression_cluster (133)
    Interaction (42)
  Map_info: Map: IV Position: -24.7527 Error: 0.274792
    Positive: Positive_clone: F56A11 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5641
    Pseudo_map_position
  Reference (36)
  Remark: the 3' end is on C18H7 (nucleotides 1 to 3,000)
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene