WormBase Tree Display for Gene: WBGene00011767

WBGene00011767 SMap: S_parent: Sequence: T14D7
  Identity: Version: 2
    Name: CGC_name: agxt-1 Person_evidence: WBPerson17942
      Sequence_name: T14D7.1
      Molecular_name: T14D7.1
        T14D7.1.1
        CE23985
        T14D7.1.2
      Other_name: CELE_T14D7.1 Accession_evidence: NDB BX284602
      Public_name: agxt-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 04 Sep 2015 11:19:37 WBPerson2970 Name_change: CGC_name: agxt-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: agxt
    Allele: WBVar00752691
      WBVar00752692
      WBVar00752693
      WBVar01499702
      WBVar00752694
      WBVar00752695
      WBVar00372922
      WBVar00372923
      WBVar00372924
      WBVar00372925
      WBVar00372926
      WBVar00372927
      WBVar00372928
      WBVar00372929
      WBVar00372930
      WBVar01498435
      WBVar02033446
      WBVar00317988
      WBVar00226479
      WBVar01499017
      WBVar02012227
      WBVar00321683
      WBVar02002879
      WBVar01474174
      WBVar01696017
      WBVar01252284
      WBVar01490998
      WBVar01308846
      WBVar01308847
      WBVar02049439
      WBVar01498748
      WBVar00238325
      WBVar01498940
      WBVar00174210
      WBVar01604383
      WBVar00174212
      WBVar00174213
      WBVar00319851
      WBVar00752680
      WBVar00752681
      WBVar00752682
      WBVar00752683
      WBVar00752684
      WBVar00752685
      WBVar00752686
      WBVar00752687
      WBVar00752688
      WBVar00752689
      WBVar00104711
      WBVar00752690
    Strain: WBStrain00003009
    RNASeq_FPKM (74)
    GO_annotation: 00086956
      00086957
      00086958
      00086959
      00086960
      00086961
      00086962
      00086963
      00086964
      00086965
    Ortholog (34)
    Paralog: WBGene00009177 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: T14D7.1 is orthologous to the human gene ALANINE-GLYOXYLATE AMINOTRANSFERASE HOMOLOG (AGXT; OMIM:604285), which when mutated leads to disease. Paper_evidence: WBPaper00004637
          Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables alanine-glyoxylate transaminase activity. Involved in glycine biosynthetic process, by transamination of glyoxylate. Located in mitochondrion. Human ortholog(s) of this gene implicated in primary hyperoxaluria type 1. Is an ortholog of human AGXT (alanine--glyoxylate aminotransferase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111670 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:341)
  Molecular_info: Corresponding_CDS: T14D7.1
    Corresponding_transcript: T14D7.1.1
      T14D7.1.2
    Other_sequence: MH10589
      EY465012.1
      ES413239.1
      XI04547
      EX561424.1
      CR00384
      Hbac_isotig01890
      HC04994
      EY473594.1
      SR01328
      ACC35129_1
      GRC03486_1
      FK805624.1
      GP03346
      CBC16019_1
      DAC00900_1
      ES740197.1
      Oden_isotig03388
      MJ02231
      MCC00238_1
      EY459750.1
      Dviv_isotig25539
      GR11047
      PPC04529_1
      MPC00004_1
      Oden_isotig25868
      EZ421807.1
      CJC08145_1
      MP00143
      FC543552.1
      EY470121.1
      Tcir_isotig23589
      FK800353.1
      CBC06989_1
      Acan_isotig06010
      FD517622.1
      CBC05063_1
      EY473047.1
      FC809597.1
      ACC11108_1
      FK802863.1
      EX554677.1
      SS01263
      MIC00356_1
      EX559409.1
      EY459959.1
      MJC00779_1
      SSC00803_1
      HGC00022_1
      CSC01911_1
      MC04369
      MC00939
      MCC04459_1
      HCC06405_1
      Tcir_isotig11903
      EY463713.1
      GT736460.1
      BXC01683_1
      DA04696
      MHC03107_1
      EY462197.1
      Tcol_isotig09972
      Acan_isotig06011
      SSC03337_1
      EX557118.1
      FK801313.1
      HG03401
      MJC01250_1
      MC01235
      HG02810
      HG09843
      ACC11683_1
      SSC01622_1
      Tcir_isotig30829
      MHC09768_1
      ES742893.1
      EX555505.1
      Tcol_isotig08824
      GPC02690_1
      Tcol_isotig09973
      AF339100.1
      FK808823.1
      MJ00198
      BXC01495_1
      MCC04432_1
      XIC05072_1
      EY469482.1
      EY466422.1
      FC814904.1
      SRC00236_1
      Tcir_isotig08507
      MH00978
      MI00662
      EL890306.1
      CRC02152_1
      EY471911.1
      HBC02815_1
      PVC04253_1
      HGC07967_1
      ES409379.1
      EY464162.1
      Oden_isotig03389
    Associated_feature: WBsf658006
      WBsf658007
      WBsf658008
      WBsf658009
      WBsf988838
      WBsf221823
      WBsf221824
  Experimental_info: RNAi_result: WBRNAi00053319 Inferred_automatically: RNAi_primary
      WBRNAi00035565 Inferred_automatically: RNAi_primary
      WBRNAi00018708 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram797
      Expr6693
      Expr15739
      Expr1015563
      Expr1035181
      Expr1156904
      Expr2009267
      Expr2027504
    Drives_construct: WBCnstr00003509
    Microarray_results (19)
    Expression_cluster (131)
    Interaction (24)
  Map_info: Map: II Position: 0.905429
    Positive: Positive_clone: T14D7 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00049683
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene