WormBase Tree Display for Gene: WBGene00020788

WBGene00020788 SMap: S_parent: Sequence: T25B6
  Identity: Version: 2
    Name: CGC_name: nep-22 Person_evidence: WBPerson260
      Sequence_name: T25B6.2
      Molecular_name: T25B6.2
        T25B6.2.1
        CE14174
      Other_name: CELE_T25B6.2 Accession_evidence: NDB BX284606
      Public_name: nep-22
    DB_info: Database: AceView gene XJ655
        WormQTL gene WBGene00020788
        WormFlux gene WBGene00020788
        NDB locus_tag CELE_T25B6.2
        Panther gene CAEEL|WormBase=WBGene00020788|UniProtKB=Q22763
          family PTHR11733
        NCBI gene 181144
        RefSeq protein NM_077127.5
        TREEFAM TREEFAM_ID TF318791
        TrEMBL UniProtAcc Q22763
        UniProt_GCRP UniProtAcc Q22763
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:03 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 10 Feb 2012 15:49:10 WBPerson2970 Name_change: CGC_name: nep-22
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nep
    Allele: WBVar00094414 Inferred_automatically: From strain object: RB2463
      WBVar02139787
      WBVar02056550
      WBVar01487391
      WBVar01171515
      WBVar01171516
      WBVar01171517
      WBVar01171518
      WBVar01171519
      WBVar01171520
      WBVar01171521
      WBVar01171522
      WBVar01171523
      WBVar01171524
      WBVar01171525
      WBVar01171526
      WBVar01171527
      WBVar01171528
      WBVar01171529
      WBVar01171530
      WBVar01171531
      WBVar01171532
      WBVar01171533
      WBVar01171534
      WBVar01171535
      WBVar01171536
      WBVar01171537
      WBVar01171538
      WBVar02065447
      WBVar02150744
      WBVar01894627
      WBVar01602071
      WBVar01602072
      WBVar00081735
      WBVar00081736
      WBVar01499963
      WBVar02086823
      WBVar01550827
      WBVar01550828
      WBVar02125399
      WBVar01473763
      WBVar01886528
      WBVar01886529
      WBVar01886530
      WBVar01886531
      WBVar01886532
      WBVar01499642
      WBVar01498722
      WBVar00511955
      WBVar00511956
      WBVar00511957
      WBVar01782545
      WBVar00511958
      WBVar01782546
      WBVar00511959
      WBVar00511960
      WBVar00511961
      WBVar00511962
      WBVar00511963
      WBVar01981155
      WBVar01497108
      WBVar01849536
      WBVar01849537
      WBVar01849538
      WBVar01849539
      WBVar01491414
      WBVar01849540
      WBVar01498960
      WBVar01500067
    Strain: WBStrain00033138
      WBStrain00037406
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog: WBGene00051084 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00023645 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00159450 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00125963 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00096502 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00089596 Pristionchus pacificus From_analysis: OMA
      CBOVI.g2801 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g11544 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g19577 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g3611 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g4312 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g21379 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g9085 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g14365 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g26099 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g18010 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00143.g5516 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_20112.g26391 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-nep-22 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g18727 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00108.g4515 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_03474 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_025053 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g01789 Oscheius tipulae From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g11413 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g21809 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0183600 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g19682 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00275364 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00284006 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00263974 Strongyloides ratti From_analysis: WormBase-Compara
    Paralog (24)
    Structured_description: Concise_description: nep-22 encodes two isoforms of a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; NEP-22 is orthologous to Ac-mep-1, a gut luminal neprilysin which is specifically expressed in the adult life stage of Ancylostoma caninum hookworms, and whose protein product is localized to the microvilli of the gastrointestinal tract, suggesting a role in digestion. Paper_evidence: WBPaper00004584
            WBPaper00012962
            WBPaper00013276
          Curator_confirmed: WBPerson567
          Date_last_updated: 27 Mar 2014 00:00:00
      Automated_description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Located in membrane raft. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T25B6.2
    Corresponding_CDS_history: T25B6.2a:wp142
      T25B6.2b:wp142
    Corresponding_transcript: T25B6.2.1
    Other_sequence (102)
    Associated_feature: WBsf648394
      WBsf236116
      WBsf236117
      WBsf236118
  Experimental_info: RNAi_result: WBRNAi00054097 Inferred_automatically: RNAi_primary
      WBRNAi00000575 Inferred_automatically: RNAi_primary
      WBRNAi00035945 Inferred_automatically: RNAi_primary
      WBRNAi00089168 Inferred_automatically: RNAi_primary
      WBRNAi00019187 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1019959
      Expr1039054
      Expr1157641
      Expr2013967
      Expr2032206
    Drives_construct: WBCnstr00024887
    Construct_product: WBCnstr00024887
    Microarray_results (19)
    Expression_cluster (260)
    Interaction (40)
  Map_info: Map: X Position: 0.573562
    Positive: Positive_clone: T25B6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00011415
    WBPaper00011735
    WBPaper00029046
    WBPaper00037777
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene