WormBase Tree Display for Gene: WBGene00018426

WBGene00018426 SMap: S_parent: Sequence: F44E7
  Identity: Version: 1
    Name: Sequence_name: F44E7.4
      Molecular_name (12)
      Other_name: CELE_F44E7.4 Accession_evidence: NDB BX284605
      Public_name: F44E7.4
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele: WBVar01499154
      WBVar01499528
      WBVar00262058
      WBVar02150332
      WBVar01808131
      WBVar01808132
      WBVar01808133
      WBVar01499740
      WBVar01808134
      WBVar01808135
      WBVar01651690
      WBVar01491100
      WBVar01740330
      WBVar01740331
      WBVar01740332
      WBVar01014244
      WBVar01500129
      WBVar01014245
      WBVar01014246
      WBVar01014247
      WBVar01014248
      WBVar01014249
      WBVar01014250
      WBVar01014251
      WBVar01014252
      WBVar01014253
      WBVar01014254
      WBVar01014255
      WBVar01014256
      WBVar01014257
      WBVar01014258
      WBVar01014259
      WBVar01014260
      WBVar01014261
      WBVar01014262
      WBVar01460032
      WBVar01014263
      WBVar01460033
      WBVar00459101
      WBVar00209756
      WBVar00459102
      WBVar00209757
      WBVar00459103
      WBVar00459104
      WBVar00209758
      WBVar00459105
      WBVar00209759
      WBVar00459106
      WBVar01973628
      WBVar00459107
      WBVar00459108
      WBVar00459109
      WBVar00459110
      WBVar00459111
      WBVar02136397
      WBVar00598896
      WBVar00598897
      WBVar01588322
      WBVar01499864
      WBVar01499496
      WBVar01499865
      WBVar01499316
      WBVar02154273
      WBVar01500066
    RNASeq_FPKM (74)
    GO_annotation: 00027573
      00027574
      00027575
      00027576
      00027577
      00027578
      00027579
      00027580
      00027581
      00123575
    Contained_in_operon: CEOP5565
    Ortholog (40)
    Paralog (11)
    Structured_description: Automated_description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in peptide catabolic process and proteolysis involved in protein catabolic process. Predicted to be located in cytosol and mitochondrion. Expressed in gonad. Human ortholog(s) of this gene implicated in Alzheimer's disease; diabetic encephalopathy; and type 2 diabetes mellitus. Is an ortholog of human IDE (insulin degrading enzyme). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5381)
      DOID:0050850 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5381)
      DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5381)
  Molecular_info: Corresponding_CDS: F44E7.4a
      F44E7.4b
      F44E7.4c
      F44E7.4d
    Corresponding_transcript: F44E7.4a.1
      F44E7.4b.1
      F44E7.4c.1
      F44E7.4d.1
    Other_sequence (23)
    Associated_feature: WBsf652650
      WBsf652651
      WBsf1000085
      WBsf233722
      WBsf233723
  Experimental_info: RNAi_result: WBRNAi00014943 Inferred_automatically: RNAi_primary
      WBRNAi00014942 Inferred_automatically: RNAi_primary
      WBRNAi00047301 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr4017
      Expr1022310
      Expr1037941
      Expr1151157
      Expr2003723
      Expr2021942
    Drives_construct: WBCnstr00026526
    Construct_product: WBCnstr00026526
    Microarray_results: SMD_F44E7.3
      SMD_F44E7.4
      188575_s_at
      A_12_P105300
      A_12_P109503
      A_12_P150205
      A_12_P150206
      A_12_P158026
      Aff_F44E7.4
      GPL13394_WBGene00018426
      GPL13914_F44E7.4
      GPL14144_F44E7.4a_2683-2742_0.898_19_B
      GPL14144_F44E7.4a_2837-2896_0.823_112_C
      GPL14144_F44E7.4a_3015-3074_0.944_2_A
      GPL19516_CGZ0021652
      GPL19516_CGZ0021653
      GPL19516_CGZ0021654
      GPL19516_CGZ0021655
      GPL19516_CGZ0021656
      GPL21109_F44E7.4a
      GPL21109_F44E7.4d
      GPL3518_CE10402
      GPL8304_CE_WBGene00018426_A
      GPL8304_CE_WBGene00018426_C
      GPL8673_F44E7_4aP01923
      GPL8673_F44E7_4aP02619
      GPL8673_F44E7_4aP02952
      GPL8673_F44E7_4bP01923
      GPL8673_F44E7_4bP02571
      GPL8673_F44E7_4bP02904
      GPL8673_F44E7_4cP01746
      GPL8673_F44E7_4cP02442
      GPL8673_F44E7_4cP02775
      GPL8673_F44E7_4dP01923
      GPL8673_F44E7_4dP02619
      GPL8673_F44E7_4dP02627
    Expression_cluster (140)
    Interaction (175)
  Map_info: Positive: Positive_clone: F44E7 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: V -0.99921
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene