WormBase Tree Display for Gene: WBGene00001340

WBGene00001340 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 1
    Name: CGC_name: etr-1 Person_evidence: WBPerson261
      Sequence_name: T01D1.2
      Molecular_name (70)
      Other_name: CELE_T01D1.2 Accession_evidence: NDB BX284602
      Public_name: etr-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:24 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: etr
    Allele: WBVar00697049
      WBVar02039822
      WBVar00697050
      WBVar00697051
      WBVar02028556
      WBVar00697052
      WBVar00697053
      WBVar00697054
      WBVar00697055
      WBVar00697056
      WBVar01474097
      WBVar00697057
      WBVar00697058
      WBVar00697059
      WBVar00697060
      WBVar00697061
      WBVar00095677
      WBVar00697062
      WBVar00697063
      WBVar00697064
      WBVar00697065
      WBVar00697066
      WBVar00697067
      WBVar01681552
      WBVar00697068
      WBVar01681553
      WBVar01681554
      WBVar00697069
      WBVar01681555
      WBVar00697070
      WBVar01681556
      WBVar00697071
      WBVar01681557
      WBVar00697072
      WBVar00697073
      WBVar01681558
      WBVar00697074
      WBVar01681559
      WBVar00697075
      WBVar00697076
      WBVar00697077
      WBVar00697078
      WBVar01412404
      WBVar00697079
      WBVar00697080
      WBVar00697081
      WBVar00697082
      WBVar00697083
      WBVar00697084
      WBVar00697085
      WBVar00697086
      WBVar00697087
      WBVar01500106
      WBVar00697088
      WBVar00697089
      WBVar00697090
      WBVar01399462
      WBVar01399463
      WBVar01498661
      WBVar01476776
      WBVar01958922
      WBVar01817565
      WBVar01500158
      WBVar01500159
      WBVar00277149
      WBVar01490970
      WBVar00354244
      WBVar01532486
      WBVar00354245
      WBVar01532487
      WBVar01532488
      WBVar00354246
      WBVar00354247
      WBVar00009041
      WBVar00354248
      WBVar00354249
      WBVar00009046
      WBVar00354250
      WBVar00354251
      WBVar00354252
      WBVar00354253
      WBVar00354254
      WBVar02129190
      WBVar00354255
      WBVar02129191
      WBVar00354256
      WBVar02129192
      WBVar02129193
      WBVar01988573
      WBVar00162865
      WBVar00162867
      WBVar01988574
      WBVar01623000
      WBVar01623001
      WBVar02017208
      WBVar01715456
      WBVar01715457
      WBVar01715458
      WBVar01715459
      WBVar01236940
      WBVar00697027
      WBVar00697028
      WBVar00697029
      WBVar00697030
      WBVar00697031
      WBVar00697032
      WBVar00697033
      WBVar01236951
      WBVar00697034
      WBVar00697035
      WBVar01291086
      WBVar01762461
      WBVar00697036
      WBVar02006350
      WBVar00697037
      WBVar01291087
      WBVar01291088
      WBVar00697038
      WBVar01291089
      WBVar00697039
      WBVar00697040
      WBVar01291092
      WBVar00697041
      WBVar00697042
      WBVar00697043
      WBVar00697044
      WBVar00697045
      WBVar00697046
      WBVar00697047
      WBVar00697048
    Possibly_affected_by: WBVar02152955
      WBVar02152954
    Strain (2)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Ortholog (43)
    Paralog (13)
    Structured_description: Concise_description: etr-1 encodes a muscle-specific ELAV-type RNA-binding protein, whose homologs include Drosophila ELAV and human CUG-BINDING PROTEIN (CUGBP1; OMIM:601074); etr-1 function is required for embryonic muscle development, which suggests that ETR-1's homology to CUG-BP (implicated in myotonic dystrophy) might reflect conserved roles in development. Paper_evidence: WBPaper00003747
            WBPaper00005068
            WBPaper00012788
            WBPaper00012830
            WBPaper00012882
            WBPaper00012897
            WBPaper00013003
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable mRNA 3'-UTR binding activity. Involved in determination of adult lifespan. Located in nucleus. Expressed in body wall musculature; cloacal sphincter muscle; copulatory spicule; non-striated muscle; and somatic gonad. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 97. Is an ortholog of human CELF1 (CUGBP Elav-like family member 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0070383 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2550)
  Molecular_info: Corresponding_CDS (19)
    Corresponding_CDS_history: T01D1.2b:wp182
      T01D1.2c:wp247
    Corresponding_transcript (32)
    Other_sequence (57)
    Associated_feature (19)
  Experimental_info: RNAi_result (25)
    Expr_pattern: Expr1204
      Expr9488
      Expr13464
      Expr1026122
      Expr1030819
      Expr1155747
      Expr2011378
      Expr2029614
    Drives_construct: WBCnstr00010149
      WBCnstr00036992
    Construct_product: WBCnstr00014053
      WBCnstr00036992
    Regulate_expr_cluster: WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062325:muscle_depleted_noncoding-RNA
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062325:muscle_enriched_noncoding-RNA
    Antibody: WBAntibody00002767
    Microarray_results: SMD_T01D1.2
      172031_x_at
      174097_at
      192227_s_at
      A_12_P120167
      A_12_P152070
      A_12_P152071
      A_12_P152072
      A_12_P152073
      A_12_P152074
      A_12_P153655
      A_12_P153656
      A_12_P153657
      A_12_P153658
      Aff_T01D1.2A
      GPL13394_WBGene00001340
      GPL13914_T01D1.2
      GPL14144_T01D1.2f_1543-1602_0.947_2_B
      GPL14144_T01D1.2f_1602-1661_0.936_4_C
      GPL14144_T01D1.2f_1720-1779_0.958_1_A
      GPL19516_CGZ0032610
      GPL19516_CGZ0032611
      GPL19516_CGZ0032612
      GPL19516_CGZ0032613
      GPL19516_CGZ0032614
      GPL19516_CGZ0032615
      GPL19516_CGZ0032616
      GPL19516_CGZ0032617
      GPL19516_CGZ0032618
      GPL19516_CGZ0032619
      GPL19516_CGZ0032620
      GPL19516_CGZ0032621
      GPL19516_CGZ0032622
      GPL19516_CGZ0032623
      GPL19516_CGZ0032624
      GPL19516_CGZ0032625
      GPL19516_CGZ0032626
      GPL19516_CGZ0032627
      GPL19516_CGZ0032628
      GPL19516_CGZ0032629
      GPL19516_CGZ0032630
      GPL19516_CGZ0032631
      GPL19516_CGZ0032632
      GPL19516_CGZ0032633
      GPL19516_CGZ0032634
      GPL19516_CGZ0032635
      GPL19516_CGZ0032636
      GPL19516_CGZ0032637
      GPL19516_CGZ0032638
      GPL19516_CGZ0032639
      GPL19516_CGZ0032640
      GPL21109_T01D1.2a.1
      GPL21109_T01D1.2a.2
      GPL21109_T01D1.2a.3
      GPL21109_T01D1.2e.4
      GPL3518_CE12942
      GPL3518_CE28070
      GPL8304_CE_WBGene00001340_A
      GPL8304_CE_WBGene00001340_B
      GPL8304_CE_WBGene00001340_C
      GPL8673_T01D1_2aP00255
      GPL8673_T01D1_2aP00894
      GPL8673_T01D1_2aP00904
      GPL8673_T01D1_2bP00552
      GPL8673_T01D1_2bP00704
      GPL8673_T01D1_2bP00718
      GPL8673_T01D1_2cP00006
      GPL8673_T01D1_2cP00075
      GPL8673_T01D1_2cP00133
      GPL9450_T01D1.2a
      GPL9450_T01D1.2b
      cea2.3.22250
      cea2.d.05181
      cea2.d.05182
    Expression_cluster (115)
    Interaction (42)
  Map_info: Map: II Position: -15.9026 Error: 0.013546
    Positive: Positive_clone: T01D1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (23)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene