WormBase Tree Display for Gene: WBGene00020112

WBGene00020112 SMap: S_parent: Sequence: R151
  Identity: Version: 2
    Name: CGC_name: pfd-5 Person_evidence: WBPerson3663
            WBPerson2136
      Sequence_name: R151.9
      Molecular_name: R151.9
        R151.9.1
        CE00827
      Other_name: 3H288 Accession_evidence: EMBL AF303258
        CELE_R151.9 Accession_evidence: NDB BX284603
      Public_name: pfd-5
    DB_info: Database: AceView gene 3I288
        WormQTL gene WBGene00020112
        WormFlux gene WBGene00020112
        NDB locus_tag CELE_R151.9
        Panther gene CAEEL|WormBase=WBGene00020112|UniProtKB=Q21993
          family PTHR12674
        NCBI gene 176013
        RefSeq protein NM_066181.6
        SwissProt UniProtAcc Q21993
        TREEFAM TREEFAM_ID TF106509
        UniProt_GCRP UniProtAcc Q21993
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 02 Aug 2006 11:39:27 WBPerson2970 Name_change: CGC_name: pfd-5
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pfd
    Allele: WBVar00837961
      WBVar00837962
      WBVar00837963
      WBVar00837964
      WBVar00837965
      WBVar00837966
      WBVar00837967
      WBVar01500260
      WBVar01541819
      WBVar00401256
      WBVar00059560
      WBVar00146030
      WBVar01499774
      WBVar01837779
      WBVar01667472
      WBVar01628722
      WBVar01446575
      WBVar01722860
      WBVar01722861
    Strain: WBStrain00001158
      WBStrain00036684
    RNASeq_FPKM (74)
    GO_annotation: 00073616
      00073617
      00073618
      00073619
      00073620
      00124826
      00124827
      00124828
    Contained_in_operon: CEOP3420
    Ortholog (31)
    Paralog: WBGene00018071 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: pfd-5 encodes a putative prefoldin 5 subunit, orthologous to human PFDN5 (OMIM:604899), that is required for normal microtubule growth, embryonic and larval viability, fertility, vulval development, and locomotion; PFD-5 is expressed in most, if not all, tissues; pfd-5(RNAi) animals show sterile progeny, larval arrest or lethality, uncoordination, and abnormal body shapes, and pfd-5(RNAi) embryos show a reduced microtubule growth rate. Paper_evidence: WBPaper00004403
            WBPaper00005654
            WBPaper00006395
            WBPaper00024497
            WBPaper00025054
            WBPaper00031309
            WBPaper00031362
            WBPaper00031363
          Curator_confirmed: WBPerson567
          Date_last_updated: 14 Jan 2008 00:00:00
      Automated_description: Predicted to enable unfolded protein binding activity. Predicted to be involved in RNA polymerase I assembly; RNA polymerase II core complex assembly; and RNA polymerase III assembly. Predicted to be located in cytoplasm. Predicted to be part of prefoldin complex. Expressed in body wall musculature; head muscle; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human PFDN5 (prefoldin subunit 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: R151.9
    Corresponding_transcript: R151.9.1
    Other_sequence (24)
    Associated_feature: WBsf651181
      WBsf666471
      WBsf226932
  Experimental_info: RNAi_result: WBRNAi00067299 Inferred_automatically: RNAi_primary
      WBRNAi00002818 Inferred_automatically: RNAi_primary
      WBRNAi00026126 Inferred_automatically: RNAi_primary
      WBRNAi00051983 Inferred_automatically: RNAi_primary
      WBRNAi00067873 Inferred_automatically: RNAi_primary
      WBRNAi00002660 Inferred_automatically: RNAi_primary
      WBRNAi00009079 Inferred_automatically: RNAi_primary
      WBRNAi00034943 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr7840
      Expr1025899
      Expr1038748
      Expr1155625
      Expr2014845
      Expr2033080
    Drives_construct: WBCnstr00002050
      WBCnstr00025366
    Construct_product: WBCnstr00025366
    Microarray_results (19)
    Expression_cluster (110)
    Interaction: WBInteraction000006753
      WBInteraction000007327
      WBInteraction000029137
      WBInteraction000038734
      WBInteraction000039658
      WBInteraction000039810
      WBInteraction000040841
      WBInteraction000043312
      WBInteraction000046355
      WBInteraction000047251
      WBInteraction000048424
      WBInteraction000048536
      WBInteraction000049564
      WBInteraction000050449
      WBInteraction000052477
      WBInteraction000101870
      WBInteraction000101974
      WBInteraction000105733
      WBInteraction000120206
      WBInteraction000134609
      WBInteraction000198545
      WBInteraction000216760
      WBInteraction000227921
      WBInteraction000251337
      WBInteraction000275213
      WBInteraction000279977
      WBInteraction000283442
      WBInteraction000302225
      WBInteraction000309525
      WBInteraction000331147
      WBInteraction000346266
      WBInteraction000361599
      WBInteraction000370433
      WBInteraction000378201
      WBInteraction000378202
      WBInteraction000378203
      WBInteraction000379177
      WBInteraction000390925
      WBInteraction000396399
      WBInteraction000396400
      WBInteraction000396401
      WBInteraction000397299
      WBInteraction000397682
      WBInteraction000397748
      WBInteraction000401633
      WBInteraction000423729
      WBInteraction000423730
      WBInteraction000434955
      WBInteraction000435708
      WBInteraction000444854
      WBInteraction000453920
      WBInteraction000457217
      WBInteraction000458124
      WBInteraction000462015
      WBInteraction000465065
      WBInteraction000465066
      WBInteraction000465067
      WBInteraction000465068
      WBInteraction000466453
      WBInteraction000467047
      WBInteraction000467048
      WBInteraction000467049
      WBInteraction000467050
      WBInteraction000468125
      WBInteraction000468725
      WBInteraction000470690
      WBInteraction000470802
      WBInteraction000471541
      WBInteraction000471909
      WBInteraction000472144
      WBInteraction000472258
      WBInteraction000473206
      WBInteraction000473496
      WBInteraction000473913
      WBInteraction000474578
      WBInteraction000474825
      WBInteraction000475167
      WBInteraction000475465
      WBInteraction000511856
      WBInteraction000511870
      WBInteraction000523298
      WBInteraction000523346
      WBInteraction000523498
      WBInteraction000554232
      WBInteraction000554615
      WBInteraction000555881
      WBInteraction000559794
      WBInteraction000575242
      WBInteraction000578148
      WBInteraction000579470
      WBInteraction000581145
  Map_info: Map: III Position: -0.772
    Positive: Positive_clone: R151 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031309
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
    WBPaper00057218
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-0.772512)
    [200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-0.769642)
  Method: Gene