WormBase Tree Display for GO_term: GO:0039579
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| GO:0039579 | Name | suppression by virus of host ISG15-protein conjugation | |
|---|---|---|---|
| Definition | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ubiquitin-like protein ISG15 conjugation to a susbtrate. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. The papain-like protease from the coronavirus cleaves ISG15 derivatives. | ||
| Synonym | Related | suppression by virus of host ISG15 activity | |
| Status | Valid | ||
| Type | Biological_process | ||
| Parent | Instance_of | GO:0039503 | |
| Attributes_of | Index | Ancestor (29) | |
| Version | Gene Ontology releases/2023-11-15 |
