WormBase Tree Display for GO_term: GO:0039554
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| GO:0039554 | Name | suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity | |
|---|---|---|---|
| Definition | Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines. | ||
| Alt_id | GO:0039539 | ||
| Synonym | Related | inhibition by virus of host MDA-5 signaling | |
| inhibition of host IFIH1/MDA5 by virus | |||
| Inhibition of host MDA5 by virus | |||
| suppression by virus of host IFIH1 signaling pathway | |||
| suppression by virus of host MDA-5 activity | |||
| suppression by virus of host MDA-5 signaling pathway | |||
| suppression by virus of host MDA-5 signalling pathway | |||
| Status | Valid | ||
| Type | Biological_process | ||
| Parent | Instance_of | GO:0039537 | |
| Attributes_of | Index | Ancestor (35) | |
| Version | Gene Ontology releases/2023-11-15 |
