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WormBase Tree Display for Expr_pattern: Expr8965

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Name Class

Expr8965Expression_ofGeneWBGene00001248
Reflects_endogenous_expression_ofWBGene00001248
Expression_dataLife_stageWBls:0000024
WBls:0000038
WBls:0000027
WBls:0000035
WBls:0000041
WBls:0000015
WBls:0000021
Anatomy_term (19)
GO_termGO:0031594
Subcellular_localizationAt the subcellular level, ELP-1::GFP was associated with adhesion sites in both males and hermaphrodites. In the hermaphrodite body wall muscle, ELP-1::GFP was associated with the muscle arms that terminate in neuromuscular junctions. The ELP-1::GFP fluorescence is found throughout the muscle arm. In males, ELP-1::GFP associated with repeating focal attachment points in the sex-specific muscles of the worm. ELP-1 expression was prominent at the adhesion sites located at the sarcolemma.
TypeReporter_gene
PatternELP-1::GFP was associated with the nine pairs of rays of the male tale. The relatively diffuse and broad band of fluorescence appears to originate from the hypodermal cells (hyp7) and one or more of the neuronal cells of the ray (RnA, RnB).
In embryos, ELP-1::GFP expression first appeared during the comma stage. As the embryo matured into the 1-1.5 fold stage, the strongest expression was seen in the hypodermal cells, with only diffuse staining throughout the rest of the embryo. During larval development, expression of the fusion protein was progressively refined to muscle, neurons and epithelial cells. In the adult, ELP-1::GFP and ELP-1(truncated)::NLS::GFP were expressed in body wall muscle, spermatheca, vulval muscle, seam cells, the intestine, touch receptor neurons (TRNs) and inner labial 1 (IL1) neurons of the head.
PictureWBPicture0000012167
WBPicture0000012168
WBPicture0000012169
WBPicture0000012170
WBPicture0000012171
RemarkPicture: Fig 3, 4, 5.
ReferenceWBPaper00032363
TransgeneWBTransgene00008681
WBTransgene00008682
WBTransgene00008683