WormBase Tree Display for Expr_pattern: Expr8551

Expr8551 Expression_of: Gene: WBGene00020647
    Reflects_endogenous_expression_of: WBGene00020647
  Expression_data: Life_stage: WBls:0000024
      WBls:0000003
      WBls:0000038
      WBls:0000027
      WBls:0000035
    Anatomy_term: WBbt:0003681 Certain
      WBbt:0005175 Certain
      WBbt:0005772 Certain
      WBbt:0006751 Partial
      WBbt:0006759 Partial
    GO_term: GO:0016604
  Subcellular_localization: In pharynx, higher magnification of the signals revealed that the fusion protein formed speckle-like intranuclear dots (or nuclear bodies) just like mammalian PQBP1.
  Type: Reporter_gene
  Pattern: After becoming adult worm, pqbp-1.1-Venus expression reduced rapidly in pharynx, while the expression continued in intestinal cells.
    During the development, somatic gonad cells expressed pqbp-1.1-Venus only from L3 to L4 stage, and adult gonads or fertilized eggs did not express pqbp-1.1-Venus.
    Pqbp-1.1 expression was also observed in head ganglion cells at L1 stage. Some neurons in the tail show weak expression of pqbp-1.1-Venus in adult worms. However, after L1 stage, expression in neurons was relatively weak in comparison to that in intestinal cells or somatic gonad, and further analysis is needed to clarify the detail.
    pqbp-1.1 was expressed from 24-cells stage to Larva stage 4 (L4). From 24 cells- to gastrulation-stage, pqbp-1.1-Venus was expressed ubiquitously. At L1 stage, neural cells in the head ganglion express the fusion protein. From late L1 stage, intestinal cells expressed pqbp-1.1-Venus strongly and the high expression continued to L4 stage. The peak of expression was observed at L3 stage. Pharyngeal cells show an almost similar pattern of expression during development, while the peak seems to be at L4 stage.
  Picture: WBPicture0000007361
    WBPicture0000007362
    WBPicture0000007363
  Remark: Picture: Figure 2, 3, 4.
  Reference: WBPaper00032449
  Transgene: WBTransgene00030562