WormBase Tree Display for Expr_pattern: Expr8182

Expr8182 Expression_of: Gene: WBGene00002246
    Reflects_endogenous_expression_of: WBGene00002246
  Expression_data: Life_stage: WBls:0000032
    Anatomy_term: WBbt:0004537 Certain
      WBbt:0004538 Certain
      WBbt:0004539 Certain
      WBbt:0004541 Certain
      WBbt:0004543 Certain
      WBbt:0004545 Certain
  Type: Reporter_gene
  Pattern: Six head neurons expressed lag-2::GFP specifically at the onset of and throughout the dauer stage. The same level of lag-2::GFP expression was observed in dauer larvae induced by dauer pheromone, starvation, or by Daf-c mutations in the three known parallel pathways, suggesting that lag-2 expression is activated downstream of the three major signalling pathways involved in dauer formation. Moreover, authors did not detect any change in the expression level of the lag-2::GFP transgene between newly induced (4 hours post-induction), and older (96 hours post-induction) dauers, suggesting that the expression of the Notch ligand is sustained throughout the dauer stage.
  Picture: WBPicture0000007793
  Remark: Picture: Figure 1A, 1B.
    Reporter gene fusion type not specified.
  Reference: WBPaper00031997
  Transgene: WBTransgene00001906