WormBase Tree Display for Expr_pattern: Expr7982
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| Expr7982 | Expression_of | Gene | WBGene00004130 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004130 | ||
| Expression_data | GO_term | GO:0005856 | |
| GO:0005865 | |||
| Subcellular_localization | Authors reexamined intracellular localization of Ce-kettin by double or triple staining with other cytoskeletal markers and found that it localized to a portion, not the entire length, of the I-bands. Triple staining of body wall muscle for actin (thin filaments), Ce-kettin (MH44), and myosin heavy chain (thick filaments) confirmed that Ce-kettin is associated with the thin filaments. However, Ce-kettin localized to a ladder-like pattern and its localization was limited to a narrow region in the middle of the bands of actin. Triple staining for actin, Ce-kettin, and vinculin (dense bodies) showed that Ce-kettin has some overlap with vinculin, but the center of the dense bodies was devoid of Ce-kettin. In addition, comparison with the location of tropomyosin showed that tropomyosin localized to the outer region on the thin filaments with minimal overlap with Ce-kettin. These results indicate that Ce-kettin is associated with a portion of the thin filaments near the dense bodies. | ||
| Type | Antibody | ||
| Picture | WBPicture0000008791 | ||
| WBPicture0000008792 | |||
| WBPicture0000008793 | |||
| Remark | Picture: Figure 3. | ||
| Reference | WBPaper00027210 | ||
| Antibody_info | WBAntibody00000028 |
