WormBase Tree Display for Expr_pattern: Expr4795
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Expr4795 | Expression_of | Gene | WBGene00001816 | |
---|---|---|---|---|
Reflects_endogenous_expression_of | WBGene00001816 | |||
Expression_data | Anatomy_term | WBbt:0005772 | Certain | |
WBbt:0005784 | Certain | |||
GO_term | GO:0030176 | |||
Subcellular_localization | In double-labeling experiments, the anti-HAF-6 antibody did not decorate the same cellular compartment as a mitochondrial antibody (anti-Complex IV). Authors did observe co-compartmentalization using anti-HAF-6 and anti-Calreticulin antibodies, indicating that HAF-6 likely resides in the endoplasmic reticulum and not in mitochondria. HAF-6 localization extended to perinuclear regions in germline tissue, which is consistent with an endoplasmic reticulum (ER) localization. However, localization of HAF-6 to the nuclear periphery was not prominent in intestinal tissue. | |||
Type | Antibody | |||
Pattern | HAF-6 was predominantly expressed in intestinal and germline tissue. | |||
Picture | WBPicture0000008801 | |||
Remark | The subcellular patterns observed in experiments using anti-HAF-6 antibody were similar to the patterns of GFP expression observed in transgenic animals expressing the HAF-6::GFP fusion protein. | |||
Reference | WBPaper00027644 | |||
Antibody_info | WBAntibody00001096 |