WormBase Tree Display for Expr_pattern: Expr3919

Expr3919 Expression_of: Gene: WBGene00001132
    Reflects_endogenous_expression_of: WBGene00001132
  Expression_data: Life_stage: WBls:0000024
      WBls:0000038
      WBls:0000027
      WBls:0000035
      WBls:0000041
      WBls:0000015
      WBls:0000021
    Anatomy_term: WBbt:0005733 Certain
      WBbt:0005813 Certain
    GO_term: GO:0005634
      GO:0005737
      GO:0005911
      GO:0032432
  Subcellular_localization: This muscle-specific localization of ALP-1A::GFP first appears as the muscle cytoskeleton is being established and continues within developing musculature throughout embryogenesis where it is detected both cytoplasmically and in the body wall muscle nuclei. Just before embryonic elongation, ALP-1A::GFP is localized to periodic circumferential fibrils in the hypodermis that persist throughout embryogenesis. This localization pattern is coincident with morphogenetic actin bundles that are required for an actin-myosin-mediated contractile process that drives morphogenesis of the embryo. ALP-1A::GFP localization at these circumferential actin bundles persists throughout morphogenesis during which the fusion protein also localizes to cell junctions in the hypodermal seam cells. Later in development, ALP-1A::GFP expression was detected at the cell-cell junctions of the hypodermal seam cells during larval stages as well.
  Type: Reporter_gene
  Pattern: The ALP-1A::GFP is expressed early in muscle development where it first appears during the comma-stage in the characteristic pair of bands that line the lateral surfaces of the embryo, demarcating the nascent body wall muscle cells. Throughout adulthood ALP-1A is most prevalent in the body wall muscle. In addition to the muscle expression, ALP-1A::GFP is expressed in the embryonic hypodermis.
  Reference: WBPaper00026945
  Transgene: WBTransgene00001778