WormBase Tree Display for Expr_pattern: Expr3686

Expr3686 Expression_of: Gene: WBGene00001345
    Reflects_endogenous_expression_of: WBGene00001345
  Expression_data: Anatomy_term: WBbt:0004522 Certain
      WBbt:0005175 Partial
      WBbt:0007831 Certain
      WBbt:0008435 Certain
    GO_term: GO:0005634
  Subcellular_localization: fos-1a::YFP-TL protein localized to the nucleus
  Type: Reporter_gene
  Pattern: Transgenic animals containing the fos-1a::YFP-TX and -TL reporters showed the same expression pattern at all times examined, and fos-1a::YFP-TL protein localized to the nucleus. fos-1a::YFP-TL also rescued the AC-invasion defect when expressed in fos-1(ar105) mutants. fos-1a was expressed at the highest level in the AC and at lower levels in neighboring somatic gonad cells during AC invasion. No expression of fos-1a was detected in vulval cells. In contrast, both the fos-1b::CFP-TX and -TL reporters directed expression in vulval cells and the AC. fos-1b::CFP-TL also drove expression in neighboring uterine cells, whereas fos-1b::CFP-TX did not, suggesting the presence of a downstream uterine enhancer element in fos-1b::CFP-TL. Unlike fos-1a expression, levels of fos-1b::CFP-TL protein were not greater in the AC compared to neighboring cells. Moreover, whereas the fos-1a reporters drove expression almost exclusively in the somatic gonad cells, the fos-1b reporters directed expression in nearly all cells at the L3 stage.
  Picture: WBPicture0000009387
  Reference: WBPaper00026611
  Transgene: WBTransgene00028815