WormBase Tree Display for Expr_pattern: Expr2945

Expr2945 Expression_of: Gene: WBGene00006545
    Reflects_endogenous_expression_of: WBGene00006545
  Expression_data: Life_stage: WBls:0000003
    Anatomy_term: WBbt:0003675 Partial
      WBbt:0005733 Partial
        Remark: Expressed in dorsal hypodermal cells and seam cells, not expressed in ventral hypodermal cells.
      WBbt:0006000 Certain
      WBbt:0006370 Certain
      WBbt:0006441 Certain
      WBbt:0006547 Certain
      WBbt:0006612 Certain
      WBbt:0006733 Certain
    GO_term: GO:0005634
  Subcellular_localization: In all cases expression was found to be nuclear.
  Type: Reporter_gene
  Pattern: tbx-8 is expressed in three different cell types in the embryo, gut, muscle and hypodermis. The earliest embryonic expression was detected in the E lineage gut cell precursors Ea and Ep at the beginning of gastrulation (100 minutes after first cleavage). Expression was seen in the direct descendents of Ea and Ep but was not obvious later in E lineage nuclei. tbx-8 was subsequently expressed in muscle and hypodermal cells. The expression of tbx-8 was stronger in dorsal hypodermal nuclei. This is particularly evident in embryos that have been co-stained with LIN-26 and GFP antibodies. Expression could also be seen in dorsal hypodermal nuclei undergoing contralateral migration following cellular intercalation, and in lateral hypodermal cells during dorsal intercalation, although expression in lateral hypodermal cells at this stage was weaker. Expression in lateral hypodermal (seam) cells could also be seen later in embryogenesis until the 1.5-fold stage. No expression was observed in ventral hypodermal cells. The earliest detectable muscle cell expression was seen around the 400-cell stage, when muscle cells were present as two rows on the left and right sides of the embryo.
  Picture: WBPicture0000007589
  Remark: No detailed description on expression pattern in other life stages.
  Reference: WBPaper00024194
  Transgene: WBTransgene00001624