WormBase Tree Display for Expr_pattern: Expr1925
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| Expr1925 | Expression_of | Gene | WBGene00001833 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00001833 | ||
| Expression_data | GO_term | GO:0000793 | |
| GO:0000796 | |||
| Subcellular_localization | This antigen localizes to the poleward faces of the metaphase plate, a pattern previously shown to correspond with the holocentric centromere of C. elegans. A double staining experiment with HCP-3, a centromeric histone H3-like protein was performed to confirmed this pattern. Although both of these proteins display a punctate staining pattern in terphase, there was no detectable overlap between the two. In contrast, examination of prophase, metaphase, and anaphase chromosomes revealed that there was nearly complete colocalization between these two proteins. These results confirm that HCP-6 localizes to the C. elegans centromere during mitosis. | ||
| Type | Antibody | Polyclonal mouse antibody against HCP-6. | |
| Picture | WBPicture0000008440 | ||
| Remark | No detailed description on cellular expression patterns. | ||
| Reference | WBPaper00005322 | ||
| Antibody_info | WBAntibody00000529 |
