WormBase Tree Display for Expr_pattern: Expr16149
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| Expr16149 | Expression_of | Gene | WBGene00003001 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00003001 | ||
| Expression_data | Anatomy_term (11) | ||
| Type | Genome_editing | ||
| Reporter_gene | |||
| Pattern | Focusing on larval development, we found that LIN-12::mNG::3xFlag was expressed in all postembryonic mesoderm progenitor cells at the 4M and 8M stages, but was only localized to the nucleus in ventral M-lineage cells, consistent with functions in dorsoventral patterning of the M lineage (Foehr & Liu, 2008). LIN-12::mNG::3xFlag was subsequently visible in somatic gonad cells and in several PN.p cells where lin-12 regulates cell fates (reviewed by Sternberg, 2005). LIN-12::mNG::3xFlag was visible at the cell membrane and in internalized punctae in the P3.p - P8.p cells but localized to the nucleus only in P5.p and P7.p. Following vulval precursor cell patterning, LIN-12::mNG::3xFlag was highly expressed in numerous somatic gonad cells, with nuclear localization in several spermatheca and uterine precursor cells. | ||
| Picture | WBPicture0000015146 | ||
| Reference | WBPaper00064269 | ||
| Variation | WBVar02157825 |
