WormBase Tree Display for Expr_pattern: Expr14917
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Expr14917 | Expression_of | Gene | WBGene00010755 | ||
---|---|---|---|---|---|
Reflects_endogenous_expression_of | WBGene00010755 | ||||
Expression_data | Life_stage | WBls:0000032 | Anatomy_term | WBbt:0005733 | |
Anatomy_term | WBbt:0005733 | Certain | |||
Life_stage | WBls:0000032 | ||||
Not_in_Anatomy_term (2) | |||||
Subcellular_localization | vglu-2::gfp is exclusively expressed in a single interneuron class, AIA, where it localizes to vesicular structures in the soma, but not along the axon. In syncytial epidermis and in uterine tissue vglu-2::gfp most prominently localizes to early endosomes, and to a lesser degree apical clathrin-coated pits, TGN, and late endosomes. | ||||
Type | Genome_editing | ||||
Reporter_gene | |||||
Pattern | While the expression of VGLU-2::GFP is similar during larval and adult stages inwell fed animals, the expression and localization pattern of VGLU-2::GFP is alteredsubstantially in dauer stage animals. Expression from the AIA neurons disappears and in the epidermis, the localization of VGLU-2::GFP appears much weaker and more diffuse. Upon recovery from the dauer stage, VGLU-2::GFP expression andlocalization resumes to the state observed in animals that have not gone through the dauer stage. Starvation alone does not affect VGLU-2::GFP expression and localization. | ||||
Reference | WBPaper00058928 | ||||
Variation | WBVar02152776 |