WormBase Tree Display for Expr_pattern: Expr13484
expand all nodes | collapse all nodes | view schema
| Expr13484 | Expression_of | Gene | WBGene00015478 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00015478 | ||
| Expression_data | Anatomy_term (43) | ||
| GO_term | GO:0030425 | ||
| GO:0043025 | |||
| GO:0097730 | |||
| GO:1990075 | |||
| Subcellular_localization | Isoform C primarily localizes to cell bodies in punctate spots and throughout the ciliary region of CSNs, with only a diffuse signal along dendritic processes. Within the ciliary region, localization of both A and C isoforms occurs in a region consistent with the periciliary membrane compartment (PCMC) and along the length of the cilium. Analysis of a strain expressing the fluorescently tagged PCMC marker kap-1 demonstrated MAPK-15 isoform C colocalization with KAP-1 in the PCMC. Analysis of a strain expressing the fluorescently tagged transition-zone marker nphp-1 demonstrated that MAPK-15 isoform C does not colocalize with NPHP-1 in the transition zone, which resides between the PCMC and cilium. | ||
| Type | Reporter_gene | ||
| Pattern | Expression of mapk- 15 isoform A-fused to gfp and C-fused to mCherry was observed in non-dye-filling (ASE, BAG, CEP, IL1, IL2, and OLQ) and dye-filling (ADL, ADF, ASH, ASI, ASJ, and ASK) head CSNs, as well as in nondye filling (PQR) and dye filling (PHA, PHB) tail CSNs. Expression was also occasionally observed in mid-body neurons (PDE). | ||
| Reference | WBPaper00051560 | ||
| Transgene | WBTransgene00024858 |
