WormBase Tree Display for Expr_pattern: Expr12601
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| Expr12601 | Expression_of | Gene | WBGene00004949 | ||
|---|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004949 | ||||
| Expression_data | Anatomy_term (50) | ||||
| Not_in_Anatomy_term | WBbt:0005784 | Life_stage | WBls:0000063 | ||
| WBbt:0006797 | Life_stage | WBls:0000063 | |||
| Type | In_situ | smFISH. Expression patterns obtained by smFISH were very similar to the ones observed with fosmid reporters. | |||
| Reporter_gene | |||||
| Pattern | sox-2 expression is restricted to subsets of neuroblasts. sox-2 is expressed relatively late in nervous system development, in the progenitor of differentiated neurons, but not in earlier neuroectodermal cells. sox-2 is also expressed in some progenitors of non-neural tissue, in the head hypodermis and the arcade cells. sox-2 is expressed in several postembryonic blast cells that are generated in the embryo. These blast cells include the B, Y, F, U and K rectal epithelial cells and the seam cells along the body. Although expression of sox-2 is absent in the terminal neurons generated by these lineages, sox-2 expression extends beyond the blast cell stage [e.g. sox-2 expression is maintained in the V5 daughters (V5a and V5p) but is lost in the next division].sox-2 is expressed in the sensory neurons AWB, AWC, IL1, IL2, URA, URB, OLL, the interneurons AIM, AIN, AVK, RIH and the motor neuron class RME. The sox-2 fosmid reporter or sox-2 smFISH did not show any expression in the germ line or oocytes of young adult worms. Expression patterns obtained by smFISH were very similar to the ones observed with fosmid reporters. | ||||
| Reference | WBPaper00047042 | ||||
| Transgene | WBTransgene00021093 |
