WormBase Tree Display for Expr_pattern: Expr11536
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| Expr11536 | Expression_of | Gene | WBGene00004368 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004368 | |||
| Expression_data | Life_stage | WBls:0000041 | ||
| WBls:0000023 | ||||
| WBls:0000018 | ||||
| WBls:0000019 | ||||
| WBls:0000020 | ||||
| WBls:0000021 | ||||
| Anatomy_term | WBbt:0004473 | Certain | ||
| WBbt:0004487 | Certain | |||
| WBbt:0004488 | Certain | |||
| WBbt:0005135 | Certain | |||
| Type | Reporter_gene | |||
| Pattern | The integrated pRIC-19::GFP reporter is expressed at high levels in the M2 neurons. Neurons of the head ganglion individually express comparatively low levels of pRIC-19::GFP in their cell bodies but, collectively, create a bright halo surrounding the pharynx. The earliest signs of expression are at approximately 450 min of development, when the pharynx primordium has already elongated and begun to form the two muscular bulbs. At this stage and until late in embryogenesis, expression of the pRIC-19::GFP reporter is present in one unidentified unbranched cell within the metacorpus. This cell may be MS.paapaap, the sister cell of M1 (M1 is the only other pharyngeal cell besides the M2's that expresses the pRIC-19::GFP reporter in the adult). Consistent with the disappearance of the GFP-positive cell in the metacorpus in late L1, MS.paapaap is a cell programmed to undergo apoptosis during development (Sulston et al., 1983). Other unique cells located in the metacorpus are the motor neuron M4, the interneuron I3, and the motor-interneuron MI. The three-fold stage is the earliest stage where the M2 axons can be unambiguously visualized using the pRIC-19::GFP reporter. At the three-fold stage, the motorneurons M1 also express considerable levels of the pRIC- 19::GFP reporter but during late embryogenesis and beyond the L1 larval stage, expression level remains high only in the M2 cell, fades away completely in the unidentified pharyngeal cell located in the metacorpus, and retains only weak expression in the cell M1. | |||
| Remark | Temporal description. | |||
| Reference | WBPaper00006025 | |||
| Transgene | WBTransgene00000455 | |||
| WBTransgene00000456 |
