WormBase Tree Display for Expr_pattern: Expr11037

Expr11037 Expression_of: Gene: WBGene00004395
    Reflects_endogenous_expression_of: WBGene00004395
  Expression_data: Life_stage: WBls:0000003
      WBls:0000023
    Anatomy_term: WBbt:0005733 Certain
      WBbt:0005753 Certain
      WBbt:0007809 Certain
    GO_term: GO:0071944
      GO:0031252
  Subcellular_localization: Consistent with the transcriptional GFP reporter ROL-3::GFP is expressed in the major hypodermal cells and excluded from seam cells. At the point when seam cells are quiescent ROL-3::GFP expression is generally diffuse across the surface of the major hypodermis. Prior to and during seam cell division however, ROL-3::GFP expression intensifies and accumulates in foci at the seam cell boundaries. ROL-3::GFP localization at the seam cell boundary is lost at the anterior seam cells as they fuse with the major hypodermis. Particularly intense ROL-3::GFP foci are observed at the leading edges of the posterior seam cells as they elongate towards one another. ROL-3 localization at the seam cell boundary persists until seam cell elongation is completed. In addition to the major hypodermal cells ROL-3::GFP expression is also detected in the anterior seam cells as they take on the major hypodermal fate at the L1 stage of development. These cells migrate to separate the vulval precursor cells (VPCs) which also express ROL-3::GFP at this stage. Expression of ROL-3::GFP in the VPC's is restricted to L1 larval stage, being rapidly reduced during the L1-L2 transition and not detected at latter stages of development.
  Type: Reporter_gene
  Reference: WBPaper00042458
  Transgene: WBTransgene00018325