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WormBase Tree Display for Expr_pattern: Expr3658

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Name Class

Expr3658Expression_ofGeneWBGene00006655
Reflects_endogenous_expression_ofWBGene00006655
Expression_dataAnatomy_termWBbt:0003828Certain
WBbt:0003829Certain
WBbt:0003883Certain
WBbt:0003884Certain
WBbt:0003885Certain
WBbt:0003886Certain
WBbt:0003887Certain
WBbt:0003888Certain
WBbt:0003889Certain
WBbt:0003890Certain
WBbt:0003995Certain
WBbt:0003997Certain
WBbt:0004364Certain
WBbt:0004365Certain
WBbt:0004366Certain
WBbt:0004382Certain
WBbt:0004383Certain
WBbt:0004431Uncertain
WBbt:0004437Uncertain
WBbt:0004438Uncertain
WBbt:0004439Uncertain
WBbt:0004444Uncertain
WBbt:0004445Uncertain
WBbt:0005117Uncertain
WBbt:0005659Certain
GO_termGO:0005634
GO:0005737
GO:0043005
Subcellular_localizationSeveral of these neurons have processes leading to the tip of the head or tail. The GFP fluorescence was also observed in form of small aggregates (0.3 um to 0.9 um) along the neuronal processes. TUB-1::GFP is localized mostly to the cytoplasm with very little signal in the nucleus. This is in contrast to results from mammalian cell culture where tubby is primarily found in the nucleus. The cytoplasmic localization suggests that either C. elegans TUB-1 only transiently functions in the nucleus or a very small proportion in the nucleus is sufficient for the function or it is required only in the cytoplasm.
TypeReporter_gene
PatternGFP expression was found in several neurons, including the ciliated amphid neurons (ASI, ADL, ASK, AWB, ASH, ASJ) in the head region and ciliated phasmid neurons (PHA and PHB) in the tail, as judged by colocalization of GFP with DiI as well as in PDE and several labial neurons in the head. Expression in neurons was visible early in developing young larvae enclosed in the egg.
PictureWBPicture0000011862
ReferenceWBPaper00026699
TransgeneWBTransgene00028795