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WormBase Tree Display for Disease_model_annotation: WBDOannot00001338

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Name Class

WBDOannot00001338Disease_termDOID:162
Disease_of_speciesHomo sapiens
Modeled_byVariationWBVar00146319
Asserted_geneWBGene00002081
Association_typeis_implicated_in
Evidence_codeGO_codeIMP
ECO_termECO:0007013
Genetic_sexhermaphrodite
Paper_evidenceWBPaper00038447
Disease_model_descriptionAnchor cell invasion into the vulval epithelium in C. elegans is an experimentally and visually accessible model of invasion through basement membrane; integrin ina-1 is a regulator of basement membrane opening, with mutants showing a basement membrane gap positioning defect.
Curator_confirmedWBPerson324
Date_last_updated18 Oct 2022 00:00:00