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WormBase Tree Display for Disease_model_annotation: WBDOannot00000758

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Name Class

WBDOannot00000758Disease_termDOID:680
Disease_of_speciesHomo sapiens
Modeled_byStrainWBStrain00047800
Association_typeis_model_of
Evidence_codeGO_codeIMP
ECO_termECO:0007013
Genetic_sexhermaphrodite
Paper_evidenceWBPaper00041727
Disease_model_descriptionTransgenic expression of human Tau-337M (the 1N4R isoform of human tau with the 337M FTDP-17 mutation) in the C. elegans strain CK1301 models human taupathy causing movement defects and GABAergic motor neuron loss.
Curator_confirmedWBPerson324
Date_last_updated22 Jun 2020 00:00:00