WormBase Tree Display for DO_term: DOID:0050638
expand all nodes | collapse all nodes | view schema
| DOID:0050638 | Name | transthyretin amyloidosis | |||
|---|---|---|---|---|---|
| Status | Valid | ||||
| Alternate_id | DOID:0050761 | ||||
| Definition | An amyloidosis that is characterized by a loss of sensation in the extremities, cardiomyopathy, nephropathy, vitreous opacities, and CNS amyloidosis resulting from abnormal deposits of amyloid protein in the body's organs and tissues and has_material_basis_in autosomal dominant inheritance of mutations in the TTR gene. | ||||
| Comment | OMIM mapping confirmed by DO. | ||||
| Synonym | Exact | ATTR amyloidosis | |||
| ATTRm amyloidosis | |||||
| Amyloidosis, hereditary, transthyretin-related | |||||
| Corino de Andrade's disease | |||||
| Familial transthyretin amyloidosis | |||||
| TTR amyloidosis | |||||
| familial amyloid polyneuropathy | |||||
| paramyloidosis | |||||
| transthyretin-related hereditary amyloidosis | |||||
| Parent | Is_a | DOID:114 | |||
| DOID:655 | |||||
| DOID:9120 | |||||
| DOID:0050736 | |||||
| DB_info | Database | OMIM | disease | 105210 | |
| Disease_model_annotation | WBDOannot00000501 | ||||
| WBDOannot00000502 | |||||
| WBDOannot00000503 | |||||
| WBDOannot00000504 | |||||
| Attribute_of | Gene_by_orthology | WBGene00011181 | |||
| WBGene00022808 | |||||
| Disease_model_strain | WBStrain00005095 | ||||
| Chemical_inducer | WBMol:00005099 | ||||
| WBMol:00007854 | |||||
| Molecule_modifier | WBMol:00003315 |
