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WormBase Tree Display for CDS: T21C12.1j

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Name Class

T21C12.1jEvidenceCurator_confirmedWBPerson1983
SMapS_parentSequenceT21C12
StructureSource_exons174
10801166
17551830
19492190
32763358
43064307
DB_infoDatabaseTrEMBLUniProtAccU4PBB4
UniProtUniProtAccU4PBB4
AlphaFoldentryU4PBB4
NCBI_proteinGI_numberGI:548948853
Protein_idCHROMOSOME_IIICDH931421
DB_remarkUNC-49 protein; contains similarity to Pfam domain PF02931 (Neurotransmitter-gated ion-channel ligand binding domain); contains similarity to Interpro domains IPR036734 (Neurotransmitter-gated ion-channel ligand-binding domain superfamily), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding domain), IPR006201 (Neurotransmitter-gated ion-channel)
OriginFrom_laboratoryHX
SpeciesCaenorhabditis elegans
PropertiesCodingCDS
Prediction_statusConfirmed
IsoformCurator_confirmedWBPerson1983
VisibleGeneWBGene00006784
Corresponding_transcriptT21C12.1j.1
Corresponding_proteinCE48604
Corresponding_PCR_productmv_AAD42382
mv_AAD42383
mv_AAD42384
mv_AAD42385
mv_AAD42386
Corresponding_oligo_setGPL19516_CGZ0035850
GPL19516_CGZ0035853
GPL21109_T21C12.1g
GPL21109_T21C12.1j
GPL3518_CE28086
GPL8673_T21C12_1cP00031
GPL8673_T21C12_1cP00463
Matching_cDNAL2_Nanopore_Roach_20941
RNAi_resultWBRNAi00027895
WBRNAi00000954
Microarray_resultsGPL19516_CGZ0035850
GPL19516_CGZ0035853
GPL21109_T21C12.1g
GPL21109_T21C12.1j
GPL3518_CE28086
GPL8673_T21C12_1cP00031
GPL8673_T21C12_1cP00463
GPL8673_T21C12_1dP00031
GPL8673_T21C12_1dP00463
Brief_identificationNeurotransmitter-gated ion-channel ligand-binding domain-containing proteinAccession_evidenceUniProtTR:U4PBB4
RNASeq_FPKM (74)
Last_reviewed26 Sep 2013 00:00:00WBPerson1983
Remark[130902 pad] unc-49 contains a single copy of a GABA receptor N terminus, followed by three tandem copies of a GABA receptor C terminus. Using a single promoter, unc-49 generates three distinct GABA-A receptor-like subunits by splicing the N terminus to each of the three C-terminal repeats. This represents an RT-PCR product that was produced where exon 6 is skipped. There is low level RNASeq data to support this.Paper_evidenceWBPaper00003576
Curator_confirmedWBPerson1983
From_analysisRNASeq_Hillier_elegans
[220323 pad] This gene annotation corresponds to the UNC-49A isoform from Bamber et al. 1999 The Caenorhabditis elegans unc-49 Locus Encodes Multiple Subunits of a Heteromultimeric GABA Receptor.Paper_evidenceWBPaper00003576
Curator_confirmedWBPerson1983
Methodcurated