WormBase Tree Display for Variation: WBVar00143102

WBVar00143102 Evidence: Paper_evidence: WBPaper00002911
  Name: Public_name: e307
    Other_name: T20G5.6.1:c.1280-1G>A
    HGVSg: CHROMOSOME_III:g.10184104C>T
  Sequence_details: SMap: S_parent: Sequence: T20G5
    Flanking_sequences: ggatttttctgccgcaaatttatgtttcca gaacaatgttatcatttatctggccggcact
    Mapping_target: T20G5
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00002911
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004145
      WBStrain00030694
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00006783
    Transcript: T20G5.6.1 VEP_consequence: splice_acceptor_variant
        VEP_impact: HIGH
        HGVSc: T20G5.6.1:c.1280-1G>A
        Intron_number: 5/7
  Isolation: Mutagen: EMS
  Genetics: Interpolated_map_position: III 2.00018
    Mapping_data: In_2_point: 55
        62
        67
        74
        3248
      In_multi_point (22)
      In_pos_neg_data: 651
  Description: Phenotype (15)
    Phenotype_not_observed: WBPhenotype:0000306 Paper_evidence: WBPaper00032190
        Curator_confirmed: WBPerson712
        Remark: Expression of ChR2-YFP in GABAergic neurons was not affected. Paper_evidence: WBPaper00032190
            Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: zxIs3 Paper_evidence: WBPaper00032190
              Curator_confirmed: WBPerson712
      WBPhenotype:0000567 Paper_evidence: WBPaper00032190
        Curator_confirmed: WBPerson712
        Remark: Dorsal coiling was not triggered in animals treated to photostimulation of ChR2-YFP in cholinergic neurons. Paper_evidence: WBPaper00032190
            Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: ChR2-YFP was activated in animals swimming in liquid, or on solid substrates, by applying 450-490 nm light. The chromophore essential fro ChR2 function was supplied by growing transgenic animals on medium containing all-trans retinal. Paper_evidence: WBPaper00032190
              Curator_confirmed: WBPerson712
          Genotype: zxIs6 Paper_evidence: WBPaper00032190
              Curator_confirmed: WBPerson712
      WBPhenotype:0001645 Paper_evidence: WBPaper00040284
        Curator_confirmed: WBPerson2987
        Remark: Table 1 Paper_evidence: WBPaper00040284
            Curator_confirmed: WBPerson2987
  Reference: WBPaper00002911
    WBPaper00040284
    WBPaper00031872
    WBPaper00000031
    WBPaper00032190
    WBPaper00016473
    WBPaper00056338
  Method: Substitution_allele