WormBase Tree Display for Variation: WBVar00143068

WBVar00143068 Name: Public_name: e257
    Other_name: CE37921:p.Arg203Gln
      F56A12.1.1:c.608G>A
    HGVSg: CHROMOSOME_V:g.14374936G>A
  Sequence_details: SMap: S_parent: Sequence: F56A12
    Flanking_sequences: gcaaagaactgaatccagtggaaaaatatc gctgagacgaaagtttccggctccgaaaac
    Mapping_target: F56A12
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00050496
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004136
      WBStrain00005888
      WBStrain00006218
      WBStrain00027367
      WBStrain00033528
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00006775
    Transcript: F56A12.1.1 (12)
  Genetics: Interpolated_map_position: V 6.28204
    Mapping_data: In_2_point: 132
        839
        1725
      In_multi_point: 150
        331
        661
        668
        947
        1175
        1176
        1178
        3024
      In_pos_neg_data: 297
        2131
        3132
  Description: Phenotype: WBPhenotype:0000002 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: fairly severe kinker, e257/Df more severe phenotypes Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
        Ease_of_scoring: ES2_Difficult_to_score: Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000093 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: 15% of hermaphrodites have third gonad arm arising from additional somatic gonad founder, "Z5". e257/Df more severe phenotypes. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000230 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: often withered tail as a result of 80% CAN migration defect; e257/Df more severe phenotypes. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000232 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: often withered tail as a result of 80% CAN migration defect; e257/Df more severe phenotypes. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000583 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: slightly dumpy; e257/Df more severe phenotypes. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000594 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: migrations other than CAN also variably defective. e257/Df more severe phenotypes. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0000643 Paper_evidence: WBPaper00000031
        Curator_confirmed: WBPerson48
      WBPhenotype:0001928 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: 15% of hermaphrodites have third gonad arm arising from additional somatic gonad founder, "Z5". e257/Df more severe phenotypes. Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000641 Person_evidence: WBPerson261
        Curator_confirmed: WBPerson712
        Remark: fairly active Person_evidence: WBPerson261
            Curator_confirmed: WBPerson712
      WBPhenotype:0001426 Paper_evidence: WBPaper00004883
        Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: arIs37 Paper_evidence: WBPaper00004883
              Curator_confirmed: WBPerson712
      WBPhenotype:0001652 Paper_evidence: WBPaper00032446
        Curator_confirmed: WBPerson2021
  Disease_info: Models_disease: DOID:14702
    Models_disease_in_annotation: WBDOannot00000238
  Reference: WBPaper00032446
    WBPaper00000031
    WBPaper00004883
    WBPaper00016590
    WBPaper00015049
    WBPaper00050496
  Method: Substitution_allele