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WormBase Tree Display for Transgene: WBTransgene00008589

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Name Class

WBTransgene00008589Public_namertIs26
Summary[hsp::osm-11; elt-2p::gfp; pha-1(+)]
Synonymosm-11(OE)
ConstructionConstructWBCnstr00008293
Coinjection_otherelt-2p::gfp (pJM#67); pha-1(+) (pBX#1)
Construction_summaryClone = pHA#294, pHA#295, and pHA#296. rtIs26 was generated by irradiation of extrachromosomal array rtEx472, which was generated by co-injection of pHA#294, pHA#295, and pHA#296 at 20 ng/l with pJM#67 (elt-2p::gfp) and pBX#1 (pha-1(+)). In the three aforementioned pHA plasmids, the PCR amplified osm-11 cDNA was inserted into NheI/SacI of pPD49.78, allowing heat shock inducible expression of the osm-11 cDNA (using the hsp-16-41 promoter).
Genetic_informationIntegrated
MapIII
PhenotypeWBPhenotype:0000641Paper_evidenceWBPaper00038400
Curator_confirmedWBPerson712
RemarkAfter heat-shock, animals displayed bouts of spontaneous and transient quiescence, during which locomotion and pharyngeal pumping ceased for several minutes regardless of the presence of food.Paper_evidenceWBPaper00038400
Curator_confirmedWBPerson712
Animals exhibited a decreased level of basal locomotion activity, which was significantly enhanced after heat-shock treatment.Paper_evidenceWBPaper00038400
Curator_confirmedWBPerson712
Caused_by_geneWBGene00003891Paper_evidenceWBPaper00038400
Curator_confirmedWBPerson712
WBPhenotype:0001072Paper_evidenceWBPaper00038400
Curator_confirmedWBPerson712
RemarkAfter heat-shock, animals displayed bouts of spontaneous and transient quiescence, during which locomotion and pharyngeal pumping ceased for several minutes regardless of the presence of food.Paper_evidenceWBPaper00038400
Curator_confirmedWBPerson712
Caused_by_geneWBGene00003891Paper_evidenceWBPaper00038400
Curator_confirmedWBPerson712
WBPhenotype:0001524Paper_evidenceWBPaper00038400
Curator_confirmedWBPerson712
RemarkWith or without heat-shock, animals displayed bouts of spontaneous and transient quiescence, during which locomotion and pharyngeal pumping ceased for several minutes regardless of the presence of food. During this period, animals failed to respond to body touch at a significantly higher percentage of the time than control animals.Paper_evidenceWBPaper00038400
Curator_confirmedWBPerson712
Caused_by_geneWBGene00003891Paper_evidenceWBPaper00038400
Curator_confirmedWBPerson712
Used_forInteractorWBInteraction000500650
WBInteraction000500651
WBInteraction000500652
WBInteraction000500653
WBInteraction000500654
WBInteraction000500657
ReferenceWBPaper00038400
WBPaper00051547
WBPaper00053808
WBPaper00054814
WBPaper00055514
SpeciesCaenorhabditis elegans