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WormBase Tree Display for Transgene: WBTransgene00005480

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Name Class

WBTransgene00005480Public_namewyEx1904
Summary[egl-20::unc-6]
Synonym(Pegl-20::unc-6#1)
ConstructionConstructWBCnstr00005403
Genetic_informationExtrachromosomal
PhenotypeWBPhenotype:0000384Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
RemarkEctopic expression of UNC-6/netrin caused DA9 axon guidance defects.Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
PenetranceIncompletePaper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
Caused_by_geneWBGene00006746Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0004857PATO:0000460Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
WBPhenotype:0000679Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
RemarkGFP::RAB-3 was displaced anteriorly and created an enlarged asynaptic zone in the posterior segment of the DA9 dorsal axon.Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
Caused_by_geneWBGene00006746Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0004857PATO:0000460Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
WBPhenotype:0001224Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
RemarkThe ectopic expression of UNC-6/netrin does not alter the dorsal axon length of DA9 from that of control animals.Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
Caused_by_geneWBGene00006746Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0004857PATO:0000460Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
Phenotype_assayGenotypewyEx1902Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
WBPhenotype:0001799Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
RemarkPosterior overexpression of UNC-6 created an enlarged asynaptic zone in the posterior segment of the DA9 dorsal axon.The average length of asynaptic regions in DA9 neurons of adults is much greater than that observed for wild-type animals as assayed by the number of GFP::RAB-3 puncta in adult animals.Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
Caused_by_geneWBGene00006746Paper_evidenceWBPaper00032163
Curator_confirmedWBPerson712
ReferenceWBPaper00032163
SpeciesCaenorhabditis elegans