WormBase Tree Display for RNAi: WBRNAi00113611
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| WBRNAi00113611 | Homol | Homol_homol | F27C8:RNAi | ||
|---|---|---|---|---|---|
| Sequence_info | PCR_product | sjj_F27C8.1 | |||
| Experiment | Treatment | Worms grown on 100 mM Glucosamine (GlcN). | |||
| Delivered_by | Bacterial_feeding | ||||
| Inhibits | Predicted_gene | F27C8.1 | Inferred_automatically | RNAi_primary | |
| Gene | WBGene00000002 | Inferred_automatically | RNAi_primary | ||
| Transcript | F27C8.1.1 | Inferred_automatically | RNAi_primary | ||
| Species | Caenorhabditis elegans | ||||
| Reference | WBPaper00045095 | ||||
| Phenotype | WBPhenotype:0000039 | Remark | Glucosamine (GlcN) at a pharmacologically relevant concentration of 100 mM extends life span in N2 animals. Impairment of aat-1-expression via RNAi abolishes GlcN-mediated life span extension. Authors subsequently show this abolishment is in an NRF2/SKN-1-dependent fashion. | ||
| Method | RNAi |
