WormBase Tree Display for Interaction: WBInteraction000549475
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| WBInteraction000549475 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00000912 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00005218 | ||||
| Construct | WBCnstr00005195 | ||||
| Other_interactor | aging | Interactor_type | Trans_regulator | ||
| Interaction_summary | "During adulthood, we observed that DAF-16::GFP nuclear localization in response to DNA damage occurs most readily at day 3 and then declines as the worms age (Fig. 1d). Also the strong DAF-16 activation in xpa-1 mutants occurs during early adulthood and then steadily declines throughout adulthood (Fig. 1d and Supplementary Fig. 2A)." | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [DAF-16::GFP] | ||||
| Transgene | |||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Negative_regulate | Life_stage | WBls:0000041 | ||
| Subcellular_localization | nucleus | ||||
| Paper | WBPaper00047070 | ||||
| Remark | Fig. 1d, Fig. S2a |
