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WormBase Tree Display for Gene: WBGene00021127

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Name Class

WBGene00021127SMapS_parentSequenceW10C8
IdentityVersion1
NameSequence_nameW10C8.4
Molecular_nameW10C8.4a
W10C8.4a.1
CE30703
W10C8.4c
CE50143
W10C8.4d
CE50184
W10C8.4c.1
W10C8.4d.1
Other_nameCELE_W10C8.4Accession_evidenceNDBBX284601
Public_nameW10C8.4
DB_infoDatabaseAceViewgene1D420
WormQTLgeneWBGene00021127
WormFluxgeneWBGene00021127
NDBlocus_tagCELE_W10C8.4
PanthergeneCAEEL|WormBase=WBGene00021127|UniProtKB=O45010
familyPTHR11571
NCBIgene189332
RefSeqproteinNM_001313518.3
NM_058655.6
NM_001313517.3
TrEMBLUniProtAccA0A0K3AWN2
A0A0K3AUA9
O45010
UniProt_GCRPUniProtAccO45010
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:04WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (30)
RNASeq_FPKM (74)
Ortholog (43)
Paralog (45)
Structured_descriptionAutomated_descriptionEnriched in excretory gland cell; pharyngeal cell; and touch receptor neurons based on tiling array; microarray; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by thirteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Human GSTA1 enables several functions, including glutathione peroxidase activity; glutathione transferase activity; and steroid delta-isomerase activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal domain; and Glutathione S-transferase, C-terminal. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS290 version of WormBase
Date_last_updated11 Sep 2023 00:00:00
Disease_infoPotential_modelDOID:2841Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4626)
DOID:2394Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4626)
Molecular_infoCorresponding_CDSW10C8.4a
W10C8.4c
W10C8.4d
Corresponding_CDS_historyW10C8.4b:wp96
W10C8.4b:wp245
W10C8.4b:wp274
Corresponding_transcriptW10C8.4a.1
W10C8.4c.1
W10C8.4d.1
Other_sequenceEX553359.1
Acan_isotig15788
FD515160.1
Tcol_isotig12548
CSC01285_1
ACC11024_1
Associated_featureWBsf648990
WBsf983003
WBsf983004
WBsf219069
Experimental_infoRNAi_resultWBRNAi00077233Inferred_automaticallyRNAi_primary
WBRNAi00036427Inferred_automaticallyRNAi_primary
WBRNAi00004464Inferred_automaticallyRNAi_primary
WBRNAi00055081Inferred_automaticallyRNAi_primary
Expr_patternExpr1025421
Expr1158617
Expr2006906
Expr2025133
Microarray_results (21)
Expression_cluster (129)
Interaction (29)
Map_infoPositivePositive_cloneW10C8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionI-5.31164
MethodGene