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WormBase Tree Display for Gene: WBGene00020887

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Name Class

WBGene00020887SMapS_parentSequenceT28B4
IdentityVersion2
NameCGC_namehic-1Person_evidenceWBPerson3235
Sequence_nameT28B4.4
Molecular_nameT28B4.4
T28B4.4.1
CE33711
T28B4.4.2
Other_nameCELE_T28B4.4Accession_evidenceNDBBX284606
Public_namehic-1
DB_infoDatabaseAceViewgeneXH216
WormQTLgeneWBGene00020887
WormFluxgeneWBGene00020887
NDBlocus_tagCELE_T28B4.4
NCBIgene189029
RefSeqproteinNM_076710.8
TREEFAMTREEFAM_IDTF317021
TrEMBLUniProtAccO17346
UniProt_GCRPUniProtAccO17346
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:03WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
211 Oct 2017 16:33:09WBPerson1983Name_changeCGC_namehic-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhic
Allele (16)
StrainWBStrain00033187
RNASeq_FPKM (74)
GO_annotation00029648
Ortholog (21)
ParalogWBGene00044574Caenorhabditis elegansFrom_analysisTreeFam
Structured_descriptionConcise_descriptionT28B4.4 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; T28B4.4 is worm-specific, weakly similar to CLC-1; T28B4.4 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.Paper_evidenceWBPaper00004961
WBPaper00005654
WBPaper00005946
WBPaper00005975
WBPaper00012856
WBPaper00018356
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be located in membrane. Expressed in cholinergic neurons; head; tail; and ventral nerve cord.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST28B4.4
Corresponding_CDS_historyT28B4.4:wp97
Corresponding_transcriptT28B4.4.1
T28B4.4.2
Other_sequenceCJC07086_1
Associated_featureWBsf654072
WBsf1005600
WBsf1005601
WBsf1023118
WBsf237498
WBsf237499
WBsf237500
Experimental_infoRNAi_resultWBRNAi00036070Inferred_automaticallyRNAi_primary
WBRNAi00054381Inferred_automaticallyRNAi_primary
WBRNAi00099692Inferred_automaticallyRNAi_primary
WBRNAi00099288Inferred_automaticallyRNAi_primary
WBRNAi00019382Inferred_automaticallyRNAi_primary
WBRNAi00099894Inferred_automaticallyRNAi_primary
WBRNAi00099490Inferred_automaticallyRNAi_primary
Expr_patternExpr14244
Expr14245
Expr1020454
Expr1157929
Expr2006598
Expr2024815
Drives_constructWBCnstr00024810
WBCnstr00040677
WBCnstr00040678
Construct_productWBCnstr00024810
WBCnstr00040678
Microarray_results (19)
Expression_cluster (166)
InteractionWBInteraction000220885
WBInteraction000262568
WBInteraction000288199
WBInteraction000383031
WBInteraction000426567
WBInteraction000559801
Map_infoMapXPosition-2.74936
PositivePositive_cloneT28B4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00055660
WBPaper00065331
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene